SCHEMBL3359285

SCHEMBL3359285

COc1ccc(-c2cnn(-c3nc(-c4ccc(O)c(C)c4O)nc(-c4ccc(O)c(C)c4O)n3)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPKAPK2 P49137 1/20 0.46
MAPT P10636 8/20 0.44
ALOX15 P16050 3/20 0.44
MAPK1 P28482 3/20 0.44
TDP1 Q9NUW8 3/20 0.44
GAA P10253 3/20 0.44
TSHR P16473 2/20 0.44
USP2 O75604 1/20 0.44
TP53 P04637 1/20 0.44
HSD17B10 Q99714 1/20 0.44
MEN1 O00255 7/20 0.42
KMT2A Q03164 7/20 0.42
ALDH1A1 P00352 5/20 0.42
KDM4E B2RXH2 5/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
NPSR1 Q6W5P4 2/20 0.40
LMNA P02545 1/20 0.40
ALOX12 P18054 1/20 0.40
ADORA2A P29274 3/20 0.40
RAB9A P51151 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3360341 0.78 MAPT (0.38) MAPKAPK2MAPTALOX15MAPK1TDP1
SCHEMBL3360290 0.72 ALDH1A1 (0.53) MAPKAPK2MAPTALDH1A1KDM4ESMN1; SMN2
SCHEMBL30772116 0.70 ESR1 (0.44) MAPTALOX15MAPK1TDP1GAA
SCHEMBL30772115 0.70 ESR1 (0.44) MAPTALOX15MAPK1TDP1GAA
SCHEMBL3696821 0.70 ESR1 (0.44) MAPTALOX15MAPK1TDP1GAA
SCHEMBL3360860 0.70 MAPT (0.39) MAPTALOX15MAPK1TDP1GAA
SCHEMBL12714322 0.69 ESR1 (0.41) MAPTALOX15MAPK1TDP1GAA
SCHEMBL3360990 0.68 MAPT (0.43) MAPTALOX15MAPK1TDP1GAA
SCHEMBL5990519 0.67 MAPKAPK2 (0.64) MAPKAPK2MAPTALOX15MAPK1TDP1
SCHEMBL13282958 0.67 USP2 (0.39) MAPTALOX15MAPK1TDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2210887-A1 Bis resorcinyl triazine derivatives as protecting agents against UV radiation ISDIN, S.A. (ES) 2010-07-28 EP disclosed
WO-2010081835-A2 BIS-RESORCINYL-TRIAZINE DERIVATIVES AS PROTECTING AGENTS AGAINST UV RADIATION ISDIN, S. A. (ES) 2010-07-22 WO disclosed