Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364123 | 0.87 | KDM4E (0.48) | KMT2AMEN1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL3365200 | 0.83 | DPP4 (0.53) | KMT2ANPC1MEN1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL3362385 | 0.83 | DPP4 (0.54) | KMT2ANPC1MEN1KDM4EALDH1A1 | |
| SCHEMBL3360363 | 0.82 | CCR3 (0.44) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL3361880 | 0.78 | DPP4 (0.47) | — | |
| SCHEMBL3361149 | 0.77 | MAPT (0.46) | KMT2AMEN1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL3361800 | 0.75 | CTSL (0.43) | KMT2ANPC1MEN1L3MBTL1MAPT | |
| SCHEMBL3362189 | 0.74 | DPP4 (0.43) | KDM4EL3MBTL1 | |
| SCHEMBL3362959 | 0.74 | DPP4 (0.40) | — | |
| SCHEMBL3361314 | 0.74 | NPC1 (0.44) | NPC1ALDH1A1HSD17B10HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |