Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.59 |
| ▸ | MAOB | P27338 | 5/20 | 0.59 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CASP2 | P42575 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FER | P16591 | 1/20 | 0.42 |
| ▸ | LTK | P29376 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isatin SCHEMBL9492880 | 0.89 | MAOA (0.65) | MAOAMAOBMAPTALDH1A1NPSR1 | |
| Phthalimide SCHEMBL2319609 | 0.83 | GSK3B (0.52) | MAOAMAOBSLC7A5MAPTALDH1A1 | |
| Anthraquinone SCHEMBL27983859 | 0.82 | SLC7A5 (0.60) | SLC7A5MAPTALDH1A1LMNAMEN1 | |
| Anthraquinone SCHEMBL3654040 | 0.82 | SLC7A5 (0.60) | SLC7A5MAPTALDH1A1LMNAMEN1 | |
| Isatin SCHEMBL10800199 | 0.81 | MAOA (0.77) | MAOAMAOBMAPTALDH1A1NPSR1 | |
| Isatin SCHEMBL13725994 | 0.81 | MAOA (0.83) | MAOAMAOBMAPTALDH1A1NPSR1 | |
| Isatin SCHEMBL27918798 | 0.79 | MAOA (0.80) | MAOAMAOBMAPTALDH1A1NPSR1 | |
| Isatin SCHEMBL27785434 | 0.79 | MAOA (0.87) | MAOAMAOBMAPTALDH1A1NPSR1 | |
| Isatin SCHEMBL27858156 | 0.79 | MAOA (0.87) | MAOAMAOBMAPTALDH1A1NPSR1 | |
| Isatin SCHEMBL28365971 | 0.79 | MAOA (0.95) | MAOAMAOBMAPTALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |