SCHEMBL3360558

SCHEMBL3360558

C=CCC(C)(F)OP(=O)(O)O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LPAR2 Q9HBW0 1/20 0.32
LPAR3 Q9UBY5 1/20 0.32
SMPD1 P17405 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17923947 0.79 LPAR2 (0.34) LPAR2LPAR3SMPD1
SCHEMBL29350960 0.76 LPAR2 (0.32) LPAR2LPAR3
SCHEMBL11316152 0.76 LPAR2 (0.32) LPAR2LPAR3SMPD1
SCHEMBL28902226 0.74 LPAR2 (0.32) LPAR2LPAR3SMPD1
SCHEMBL29053654 0.74 LPAR2 (0.36) LPAR2LPAR3SMPD1
SCHEMBL29350401 0.73 LPAR2 (0.31) LPAR2LPAR3
SCHEMBL21596998 0.72 LPAR3 (0.36) LPAR2LPAR3SMPD1
SCHEMBL17923951 0.72 LPAR3 (0.36) LPAR2LPAR3SMPD1
SCHEMBL17417095 0.72 LPAR2 (0.30) LPAR2LPAR3
SCHEMBL6525269 0.72 LMNA (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7815816-B2 Polyfluoroether-based phosphates E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-10-19 US disclosed
US-20100129668-A1 POLYFLUOROETHER-BASED PHOSPHATES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-05-27 US disclosed
US-7674928-B2 polyfluorinated phosphates used as as surfactants and additives for waterproof, oil repellent or antisoilant polymer coatings on substrates such as fibers, wood, paper, leather or stone E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-03-09 US disclosed
EP-2086989-A1 POLYFLUOROETHER-BASED PHOSPHATES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-08-12 EP disclosed
WO-2008060353-A1 POLYFLUOROETHER-BASED PHOSPHATES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-05-22 WO disclosed
US-20080113085-A1 polyfluorinated phosphates used as as surfactants and additives for waterproof, oil repellent or antisoilant polymer coatings on substrates such as fibers, wood, paper, leather or stone E. I. DU PONT DE NEMOURS AND COMPANY 2008-05-15 US disclosed