SCHEMBL3360833

SCHEMBL3360833

CN(C)P(=O)(O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL358155 0.75
SCHEMBL3270647 0.75
SCHEMBL4914754 0.75
SCHEMBL13303865 0.72
SCHEMBL696455 0.72
Hydrochloric Acid SCHEMBL11584278 0.72
Hydrochloric Acid SCHEMBL11586598 0.72 CA2 (0.43)
Hydrochloric Acid SCHEMBL8982942 0.72
SCHEMBL113460 0.72
SCHEMBL7508711 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240060068-A1 POLY-MORPHOLINO OLIGONUCLEOTIDE GAPMERS EISAI R&D MANAGEMENT CO., LTD. (JP) 2024-02-22 US claimed
EP-4259798-A1 POLY-MORPHOLINO OLIGONUCLEOTIDE GAPMERS Eisai R&D Management Co., Ltd. (JP) 2023-10-18 EP claimed
WO-2022125987-A1 POLY-MORPHOLINO OLIGONUCLEOTIDE GAPMERS EISAI R&D MANAGEMENT CO., LTD. (JP) 2022-06-16 WO claimed
EP-2623507-B1 MORPHOLINO NUCLEIC ACID DERIVATIVE NIPPON SHINYAKU CO LTD (JP) 2016-11-02 EP claimed
US-20100099159-A1 CAGED NUCLEOTIDES AND OLIGONUCLEOTIDES AND THEIR APPLICATION DEITERS ALEXANDER 2010-04-22 US claimed
EP-4608452-A2 PEPTIDE-ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS Eisai R&D Management Co., Ltd. (JP) 2025-09-03 EP disclosed
EP-4551580-A2 CRYSTALLINE MONOMERS FOR PREPARING ANTISENSE OLIGONUCLEOTIDES AND METHODS OF THEIR PREPARATION AND USE Eisai R&D Management Co., Ltd. (JP) 2025-05-14 EP disclosed
WO-2024092256-A2 PEPTIDE-ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS EISAI R&D MANAGEMENT CO., LTD. (JP) 2024-05-02 WO disclosed
EP-4330394-A2 ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS Eisai R&D Management Co., Ltd. (JP) 2024-03-06 EP disclosed
US-20240060068-A1 POLY-MORPHOLINO OLIGONUCLEOTIDE GAPMERS EISAI R&D MANAGEMENT CO., LTD. (JP) 2024-02-22 US disclosed
WO-2024010870-A2 CRYSTALLINE MONOMERS FOR PREPARING ANTISENSE OLIGONUCLEOTIDES AND METHODS OF THEIR PREPARATION AND USE EISAI R&D MANAGEMENT CO., LTD. (JP) 2024-01-11 WO disclosed
EP-4259798-A1 POLY-MORPHOLINO OLIGONUCLEOTIDE GAPMERS Eisai R&D Management Co., Ltd. (JP) 2023-10-18 EP disclosed
US-4634697-A Carboxyalkenamidocephalosporins SHIONOGI & CO., LTD. (JP) 1987-01-06 US disclosed
US-4614797-A Cephalosporin hydroxamic acids SHIONOGI & CO., LTD. (JP) 1986-09-30 US disclosed
US-4578378-A (Oxoheterocyclic carbonamido)cephem carboxylic acid derivatives SHIONOGI & CO., LTD. (JP) 1986-03-25 US disclosed
US-4569993-A BACTERICIDES SHIONOGI & CO., LTD. (JP) 1986-02-11 US disclosed
US-4532233-A Antibiotics SHIONOGI & CO., LTD. (JP) 1985-07-30 US disclosed
EP-0128536-A1 Fluoromethylthiooxacephalosporin derivatives SHIONOGI & CO., LTD. (JP) 1984-12-19 EP disclosed
EP-0117143-A2 Cephalosporin hydroxamic acids, their preparation, antibacterial formulations comprising the same, and their use in combating bacteria SHIONOGI & CO., LTD. (JP) 1984-08-29 EP disclosed
US-3937765-A REACTING A PHENOL AND A N,N-DIALKYL PHOSPHOAMIDIC HALIDE STAUFFER CHEMICAL COMPANY (US) 1976-02-10 US disclosed