Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13271093 | 0.95 | MAPT (0.36) | MAPTMAPK1GAAUSP2TP53 | |
| SCHEMBL30772115 | 0.78 | ESR1 (0.44) | MAPTMAPK1GAAUSP2TP53 | |
| SCHEMBL3696821 | 0.78 | ESR1 (0.44) | MAPTMAPK1GAAUSP2TP53 | |
| SCHEMBL30772116 | 0.78 | ESR1 (0.44) | MAPTMAPK1GAAUSP2TP53 | |
| SCHEMBL18027877 | 0.74 | MAPT (0.43) | MAPTMAPK1TP53LMNAKDM4E | |
| SCHEMBL12714322 | 0.73 | ESR1 (0.41) | MAPTMAPK1GAAUSP2TP53 | |
| SCHEMBL3469147 | 0.73 | PDE10A (0.39) | MAPTMAPK1GAAUSP2TP53 | |
| SCHEMBL3360990 | 0.73 | MAPT (0.43) | MAPTMAPK1GAAUSP2TP53 | |
| SCHEMBL3469011 | 0.73 | HDAC8 (0.42) | MAPTMAPK1GAAUSP2TP53 | |
| SCHEMBL3361268 | 0.71 | MAPT (0.41) | MAPTMAPK1GAAUSP2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210887-A1 | Bis resorcinyl triazine derivatives as protecting agents against UV radiation | ISDIN, S.A. (ES) | 2010-07-28 | — | — | EP | disclosed |
| WO-2010081835-A2 | BIS-RESORCINYL-TRIAZINE DERIVATIVES AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S. A. (ES) | 2010-07-22 | — | — | WO | disclosed |