Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 11/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13283104 | 0.90 | PDE10A (0.39) | PDE10ACYP11B1CYP11B2SLC22A12ELANE | |
| SCHEMBL30772115 | 0.76 | ESR1 (0.44) | MAPTUSP2TP53GAAALOX15 | |
| SCHEMBL30772116 | 0.76 | ESR1 (0.44) | MAPTUSP2TP53GAAALOX15 | |
| SCHEMBL3696821 | 0.76 | ESR1 (0.44) | MAPTUSP2TP53GAAALOX15 | |
| SCHEMBL13282976 | 0.75 | PDE10A (0.34) | PDE10ACYP11B1CYP11B2 | |
| SCHEMBL3469122 | 0.74 | PDE10A (0.33) | PDE10AMAPK1LMNAALDH1A1 | |
| SCHEMBL3360860 | 0.73 | MAPT (0.39) | MAPTUSP2TP53GAAALOX15 | |
| SCHEMBL3363742 | 0.72 | ALDH1A1 (0.46) | MAPTTSHRHSD17B10LMNAALDH1A1 | |
| SCHEMBL12714322 | 0.71 | ESR1 (0.41) | MAPTUSP2TP53GAAALOX15 | |
| SCHEMBL13271093 | 0.69 | MAPT (0.36) | MAPTUSP2TP53GAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081835-A2 | BIS-RESORCINYL-TRIAZINE DERIVATIVES AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S. A. (ES) | 2010-07-22 | — | — | WO | disclosed |