Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7113056 | 1.00 | ACE (0.46) | ACERENLMNACYP2C19HSD17B10 | |
| SCHEMBL10905425 | 0.86 | ACE (0.41) | ACERENLMNACYP2C19HSD17B10 | |
| SCHEMBL28439470 | 0.86 | ACE (0.41) | ACERENLMNACYP2C19HSD17B10 | |
| SCHEMBL27718628 | 0.84 | ACE (0.40) | ACERENLMNACYP2C19HSD17B10 | |
| SCHEMBL4963186 | 0.84 | ACE (0.40) | ACERENLMNACYP2C19HSD17B10 | |
| SCHEMBL28064542 | 0.84 | ACE (0.37) | ACERENLMNACYP2C19HSD17B10 | |
| SCHEMBL1356515 | 0.84 | ACE (0.40) | ACERENLMNACYP2C19HSD17B10 | |
| SCHEMBL22418322 | 0.83 | ACE (0.35) | ACE | |
| SCHEMBL27988623 | 0.82 | ATM (0.44) | ACEREN | |
| SCHEMBL2709523 | 0.82 | DPP4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8269037-B2 | Absorption medium for removing acid gases which comprises amino acid and acid promoter | BASF SE (DE) | 2012-09-18 | — | — | US | disclosed |
| US-20100186590-A1 | ABSORPTION MEDIUM FOR REMOVING ACID GASES WHICH COMPRISES AMINO ACID AND ACID PROMOTER | BASF SE (DE) | 2010-07-29 | — | — | US | disclosed |
| EP-0731788-A1 | PROLYL ENDOPEPTIDASE INHIBITORS | MERRELL PHARMACEUTICALS INC. (US) | 1996-09-18 | — | — | EP | disclosed |
| WO-1995015310-A1 | PROLYL ENDOPEPTIDASE INHIBITORS | MERRELL PHARMACEUTICALS INC. (US) | 1995-06-08 | — | — | WO | disclosed |