Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.65 |
| ▸ | DRD3 | P35462 | 12/20 | 0.65 |
| ▸ | HTR1A | P08908 | 2/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.65 |
| ▸ | DRD4 | P21917 | 2/20 | 0.65 |
| ▸ | HTR2A | P28223 | 2/20 | 0.65 |
| ▸ | HTR2C | P28335 | 2/20 | 0.65 |
| ▸ | HTR7 | P34969 | 2/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.65 |
| ▸ | HRH1 | P35367 | 2/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.65 |
| ▸ | DRD1 | P21728 | 1/20 | 0.65 |
| ▸ | DRD5 | P21918 | 1/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.64 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1774667 | 0.91 | DRD2 (0.66) | DRD2DRD3HTR1AADRA2ADRD4 | |
| SCHEMBL184341 | 0.89 | DRD2 (0.71) | DRD2DRD3HTR1AADRA2ADRD4 | |
| Bromide SCHEMBL1775020 | 0.88 | DRD2 (0.69) | DRD2DRD3HTR1AADRA2ADRD4 | |
| Hydrochloric Acid SCHEMBL183841 | 0.88 | DRD2 (0.70) | DRD2DRD3HTR1AADRA2ADRD4 | |
| Hydrochloric Acid SCHEMBL1774393 | 0.88 | DRD2 (0.70) | DRD2DRD3HTR1AADRA2ADRD4 | |
| SCHEMBL29544737 | 0.85 | DRD2 (0.68) | DRD2DRD3HTR1AADRA2ADRD4 | |
| Maleic Acid SCHEMBL1774461 | 0.84 | DRD2 (0.64) | DRD2DRD3HTR1AADRA2ADRD4 | |
| SCHEMBL29282392 | 0.82 | DRD2 (0.64) | DRD2DRD3HTR1AADRA2ADRD4 | |
| SCHEMBL3674514 | 0.82 | DRD2 (0.71) | DRD2DRD3HTR1AADRA2ADRD4 | |
| SCHEMBL18041270 | 0.82 | DRD2 (0.71) | DRD2DRD3HTR1AADRA2ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137335-A1 | METABOLITES OF (THIO) CARBAMOYL-CYCLOHEXANE DERIVATIVES | RICHTER GEDEON NYRT. (HU) | 2010-06-03 | — | — | US | disclosed |
| EP-2155707-A1 | METABOLITES OF (THIO)CARBAMOYL-CYCLOHEXANE DERIVATIVES | Richter Gedeon NYRT (HU) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008142461-A1 | METABOLITES OF (THIO)CARBAMOYL-CYCLOHEXANE DERIVATIVES | RICHTER GEDEON NYRT. (HU) | 2008-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137335-A1 | METABOLITES OF (THIO) CARBAMOYL-CYCLOHEXANE DERIVATIVES | TACR2, TACR1, CNR2 | DRD2 10/4885DRD3 37/4885HTR1A 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.