Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | SNCA | P37840 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ITGAM | P11215 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361592 | 1.00 | MAPT (0.44) | MAPTAPPSNCAMEN1KMT2A | |
| SCHEMBL14419503 | 1.00 | MAPT (0.44) | MAPTAPPSNCAMEN1KMT2A | |
| SCHEMBL1022199 | 0.83 | MAPT (0.60) | MAPTAPPSNCAMEN1KMT2A | |
| SCHEMBL1022200 | 0.83 | MAPT (0.60) | MAPTAPPSNCAMEN1KMT2A | |
| SCHEMBL4709524 | 0.83 | MAPT (0.60) | MAPTAPPSNCAMEN1KMT2A | |
| SCHEMBL13929386 | 0.81 | CNR1 (0.36) | MAPTAPPSNCAMEN1KMT2A | |
| SCHEMBL8031160 | 0.81 | MAPT (0.60) | MAPTAPPSNCAMEN1KMT2A | |
| SCHEMBL4719164 | 0.81 | MAPT (0.54) | MAPTAPPSNCAMEN1KMT2A | |
| SCHEMBL8226301 | 0.81 | MAPT (0.54) | MAPTAPPSNCAMEN1KMT2A | |
| SCHEMBL7839339 | 0.80 | FBP1 (0.46) | MAPTAPPSNCAPPARGAMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996590-B1 | SPIROINDOLINONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2010-10-06 | — | — | EP | disclosed |