SCHEMBL336169

SCHEMBL336169

O=C(O)c1cc(C(=O)O)cc(C(=O)c2cc(C(=O)O)cc(C(=O)O)c2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 5/20 0.58
TSHR P16473 3/20 0.57
ALOX15 P16050 1/20 0.57
HIF1A Q16665 1/20 0.57
CA12 O43570 2/20 0.55
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
CA7 P43166 2/20 0.55
CA9 Q16790 2/20 0.55
CA14 Q9ULX7 2/20 0.55
TPMT P51580 3/20 0.52
TP53 P04637 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
ALDH1A1 P00352 2/20 0.52
KDM4E B2RXH2 1/20 0.52
LMNA P02545 1/20 0.52
CA3 P07451 1/20 0.52
MAPT P10636 1/20 0.52
SELL P14151 1/20 0.52
HPGD P15428 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26189 0.89 CA12 (0.65) SRD5A2TSHRALOX15HIF1ACA12
SCHEMBL22982 0.89 CA12 (0.65) SRD5A2TSHRALOX15HIF1ACA12
SCHEMBL28565971 0.89 SRD5A2 (0.79) SRD5A2TSHRALOX15CA12CA1
SCHEMBL365949 0.87 SRD5A2 (0.73) SRD5A2TSHRTDP1ALDH1A1KDM4E
SCHEMBL23004950 0.86 CA12 (0.61) SRD5A2TSHRALOX15HIF1ACA12
SCHEMBL15789102 0.86 CA12 (0.61) SRD5A2TSHRALOX15HIF1ACA12
Hydrochloric Acid SCHEMBL297134 0.86 CA12 (0.61) SRD5A2TSHRALOX15HIF1ACA12
SCHEMBL21590118 0.86 CA12 (0.61) SRD5A2TSHRALOX15HIF1ACA12
Potassium SCHEMBL30862175 0.86 CA12 (0.61) SRD5A2TSHRALOX15HIF1ACA12
Benzene SCHEMBL20211008 0.86 CA12 (0.61) TSHRALOX15HIF1ACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3536729-B1 METHOD FOR FORMING A LASER-SINTERABLE POWDER 3D SYSTEMS INC (US) 2020-12-02 EP claimed
US-10450414-B2 Powder compositions and methods of manufacturing articles therefrom 3D SYSTEMS, INC. (US) 2019-10-22 US claimed
EP-3536729-A1 METHOD FOR FORMING A LASER-SINTERABLE POWDER 3D Systems, Incorporated (US) 2019-09-11 EP claimed
EP-2265673-B1 POWDER COMPOSITIONS AND METHODS OF MANUFACTURING ARTICLES THEREFROM 3D SYSTEMS INC (US) 2019-05-08 EP claimed
EP-2201059-B1 HIGH FLUIDITY POLYAMIDE RHODIA OPERATIONS (FR) 2019-05-01 EP claimed
EP-2379311-B1 POLYESTER POWDER COMPOSITIONS, METHODS AND ARTICLES 3D SYSTEMS INC (US) 2018-05-30 EP claimed
US-20170158816-A1 Powder Compositions and Methods of Manufacturing Articles Therefrom 3D SYSTEMS, INC. 2017-06-08 US claimed
US-9611355-B2 Powder compositions and methods of manufacturing articles therefrom 3D SYSTEMS, INC. (US) 2017-04-04 US claimed
US-20170015786-A1 MODIFIED POLYAMIDES HAVING ENHANCED FLOWABILITY/MECHANICAL PROPERTIES AND MOLDING COMPOSITIONS COMPRISED THEREOF RHODIA OPERATIONS (FR) 2017-01-19 US claimed
EP-2001935-B1 HIGH-FLUIDITY POLYAMIDE RHODIA OPERATIONS (FR) 2016-08-17 EP claimed
US-20120123041-A1 HIGH-VISCOSITY POLYAMIDE RHODIA OPERATIONS (FR) 2012-05-17 US claimed
US-8097684-B2 Polyamide and/or polyester matrix thermoplastic compositions and articles shaped therefrom RHODIA ENGINEERING PLASTICS S.R.L. (IT) 2012-01-17 US claimed
US-20110275760-A1 MODIFIED POLYAMIDES HAVING ENHANCED MELT FLOW INDICES RHODIA OPERATIONS (FR) 2011-11-10 US claimed
JP-2011514420-A 2011-05-06 JP claimed
US-20110052927-A1 Powder Compositions and Methods of Manufacturing Articles Therefrom VALSPAR SOURCING, INC. (US) 2011-03-03 US claimed
EP-2265673-A2 POWDER COMPOSITIONS AND METHODS OF MANUFACTURING ARTICLES THEREFROM Valspar Sourcing, Inc. (US) 2010-12-29 EP claimed
US-20090264588-A1 Modified Polyamides Having Enchanced Flowability/Mechanical Properties and Molding Compositions Comprised Thereof RHODIA OPERATIONS (FR) 2009-10-22 US claimed
WO-2009114715-A2 POWDER COMPOSITIONS AND METHODS OF MANUFACTURING ARTICLES THEREFROM VALSPAR SOURCING, INC. (US) 2009-09-17 WO claimed
US-20070060719-A1 Polyamide and/or polyester matrix thermoplastic compositions and articles shaped therefrom RHODIA ENGINEERING PLASTICS S.R.L. (IT) 2007-03-15 US claimed
US-20060270798-A1 Composition comprising a polymer matrix and a functionalized additive and items made from said composition RHODIANYL (FR) 2006-11-30 US claimed