SCHEMBL365949

SCHEMBL365949

O=C(O)c1cc(C(=O)O)cc(C(=O)c2ccccc2)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 4/20 0.73
ATM Q13315 1/20 0.73
TDP1 Q9NUW8 1/20 0.73
L3MBTL1 Q9Y468 1/20 0.73
ALDH1A1 P00352 1/20 0.70
DAO P14920 1/20 0.62
TSHR P16473 1/20 0.62
NAPRT Q6XQN6 1/20 0.62
CYP2C8 P10632 1/20 0.55
CYP2C9 P11712 1/20 0.55
KDM4E B2RXH2 1/20 0.55
AKR1C3 P42330 1/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
PBRM1 Q86U86 1/20 0.54
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
FFAR1 O14842 1/20 0.52
GABRA1 P14867 1/20 0.52
GABRB1 P18505 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28544459 0.98 SRD5A2 (0.70) SRD5A2ATMTDP1L3MBTL1ALDH1A1
SCHEMBL3349765 0.92 ATM (0.84) SRD5A2ATMTDP1L3MBTL1ALDH1A1
SCHEMBL13045507 0.92 ATM (0.84) SRD5A2ATMTDP1L3MBTL1ALDH1A1
SCHEMBL133982 0.92 ATM (0.84) SRD5A2ATMTDP1L3MBTL1ALDH1A1
SCHEMBL141056 0.88 ATM (0.86) SRD5A2ATMTDP1L3MBTL1ALDH1A1
SCHEMBL30320253 0.88 ATM (0.86) SRD5A2ATMTDP1L3MBTL1ALDH1A1
SCHEMBL28565971 0.87 SRD5A2 (0.79) SRD5A2ATMTDP1L3MBTL1DAO
SCHEMBL134300 0.87 ATM (0.95) SRD5A2ATMTDP1L3MBTL1ALDH1A1
SCHEMBL134024 0.87 ATM (0.95) SRD5A2ATMTDP1L3MBTL1ALDH1A1
Benzophenone SCHEMBL20578106 0.87 SRD5A2 (0.94) SRD5A2ATMTDP1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140336300-A1 HIGH DIMENSIONAL STABILITY POLYESTER COMPOSITIONS INVISTA NORTH AMERICA S.A R.L. (DE) 2014-11-13 US claimed
EP-2593513-A2 HIGH DIMENSIONAL STABILITY POLYESTER COMPOSITIONS Invista Technologies S.a r.l. (CH) 2013-05-22 EP claimed
CN-103080227-A High dimensional stability polyester compositions INVISTA TECHNOLOGIES SARL 2013-05-01 CN claimed
WO-2012009201-A2 HIGH DIMENSIONAL STABILITY POLYESTER COMPOSITIONS INVISTA TECHNOLOGIES S.A R.L. (CH) 2012-01-19 WO claimed
US-11739112-B2 Low temperature process for the synthesis of MOF carboxylate nanoparticles CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2023-08-29 US disclosed
CN-101379111-A Polymerizable unsaturated compound and method for producing the same WAKO PURE CHEM IND LTD (JP) 2009-03-04 CN disclosed
EP-0868488-A1 NAPHTHALENEDICARBOXYLATE CONTAINING POLYESTER BLEND COMPOSITIONS HAVING REDUCED FLUORESCENCE EASTMAN CHEMICAL COMPANY (US) 1998-10-07 EP disclosed
WO-1997023568-A1 NAPHTHALENEDICARBOXYLATE CONTAINING POLYESTER BLEND COMPOSITIONS HAVING REDUCED FLUORESCENCE EASTMAN CHEMICAL COMPANY (US) 1997-07-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739112-B2 Low temperature process for the synthesis of MOF carboxylate nanoparticles FTO, TPI1, ACP1 SRD5A2 2646/4885ATM 494/4885TDP1 1346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.