Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3360594 | 0.83 | DPP4 (0.71) | DPP4 | |
| SCHEMBL5744977 | 0.83 | DPP4 (0.70) | DPP4LMNATP53MAPT | |
| SCHEMBL11003403 | 0.83 | DPP4 (0.70) | DPP4LMNATP53MAPT | |
| SCHEMBL3360815 | 0.82 | DPP4 (1.00) | DPP4MAPT | |
| SCHEMBL5745244 | 0.80 | DPP4 (0.66) | DPP4MAPT | |
| SCHEMBL5743641 | 0.80 | DPP4 (0.66) | DPP4LMNATP53MAPT | |
| SCHEMBL13792321 | 0.80 | DPP4 (1.00) | DPP4 | |
| SCHEMBL5744663 | 0.79 | DPP4 (0.65) | DPP4LMNATP53MAPT | |
| SCHEMBL5745762 | 0.79 | DPP4 (0.65) | DPP4LMNATP53MAPT | |
| Hydrochloric Acid SCHEMBL29356163 | 0.79 | DPP4 (1.00) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |