SCHEMBL3362053

SCHEMBL3362053

NC[C@H](O)[C]=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11372978 1.00
SCHEMBL794252 1.00
SCHEMBL20530080 0.77
SCHEMBL794985 0.75
SCHEMBL6859963 0.75
SCHEMBL2542167 0.75
SCHEMBL11632142 0.71
SCHEMBL11325066 0.71
SCHEMBL3929 0.69
SCHEMBL3668694 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210107932-A1 NEOMYCIN AND PAROMOMYCIN DERIVATIVES WAYNE STATE UNIVERSITY (US) 2021-04-15 US claimed
EP-3618835-A1 APRAMYCIN DERIVATIVES Wayne State University (US) 2020-03-11 EP claimed
US-20200062793-A1 APRAMYCIN DERIVATIVES WAYNE STATE UNIVERSITY (US) 2020-02-27 US claimed
WO-2018204358-A1 APRAMYCIN DERIVATIVES WAYNE STATE UNIVERSITY (US) 2018-11-08 WO claimed
WO-2018187738-A1 NEOMYCIN AND PAROMOMYCIN DERIVATIVES WAYNE STATE UNIVERSITY (US) 2018-10-11 WO claimed
US-4117221-A AMINOACYL DERIVATIVES OF AMINOGLYCOSIDE ANTIBIOTICS SCHERING CORPORATION (US) 1978-09-26 US claimed
US-20210107932-A1 NEOMYCIN AND PAROMOMYCIN DERIVATIVES WAYNE STATE UNIVERSITY (US) 2021-04-15 US disclosed
EP-3618835-A1 APRAMYCIN DERIVATIVES Wayne State University (US) 2020-03-11 EP disclosed
US-20200062793-A1 APRAMYCIN DERIVATIVES WAYNE STATE UNIVERSITY (US) 2020-02-27 US disclosed
WO-2018204358-A1 APRAMYCIN DERIVATIVES WAYNE STATE UNIVERSITY (US) 2018-11-08 WO disclosed
WO-2018187738-A1 NEOMYCIN AND PAROMOMYCIN DERIVATIVES WAYNE STATE UNIVERSITY (US) 2018-10-11 WO disclosed
WO-2010030808-A2 NOVEL ANTIBIOTICS AGAINST RESISTANT BACTERIA UTAH STATE UNIVERSITY (US) 2010-03-18 WO disclosed
US-4873225-A 1-n-(4-amino-3-fluoro-2-hydroxybutyryl)-kanamycins ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1989-10-10 US disclosed
EP-0285526-A2 1-N-(4-Amino-3-fluoro-2-hydroxybutyryl)-kanamycins ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1988-10-05 EP disclosed
EP-0259014-A2 5-Deoxy-5-fluorokanamycin B derivatives and processes for the production thereof ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1988-03-09 EP disclosed
US-4117221-A AMINOACYL DERIVATIVES OF AMINOGLYCOSIDE ANTIBIOTICS SCHERING CORPORATION (US) 1978-09-26 US disclosed
US-4117221-A AMINOACYL DERIVATIVES OF AMINOGLYCOSIDE ANTIBIOTICS SCHERING CORPORATION (US) 1978-09-26 US disclosed
US-4002742-A 1-N-alkyl-4,6-di-(aminoglycosyl)-1,3-diaminocyclitols, methods for their manufacture, methods for their use as antibacterial agents, and compositions useful therefor SCHERING CORPORATION (US) 1977-01-11 US disclosed