Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3076690 | 0.84 | CYP3A4 (0.33) | SLC22A12 | |
| SCHEMBL3209179 | 0.84 | KDM6B (0.32) | SLC22A12 | |
| SCHEMBL3081184 | 0.77 | CHRM2 (0.31) | SLC22A12 | |
| SCHEMBL3078934 | 0.68 | SLC22A12 (0.43) | SLC22A12 | |
| SCHEMBL3089379 | 0.68 | SSTR4 (0.33) | — | |
| SCHEMBL3089405 | 0.67 | IDO1 (0.41) | TDP1 | |
| SCHEMBL3362475 | 0.67 | SLC22A12 (0.36) | SLC22A12 | |
| SCHEMBL3080335 | 0.66 | AOC3 (0.40) | SLC22A12 | |
| SCHEMBL4755993 | 0.64 | SLC22A12 (0.48) | SLC22A12TDP1 | |
| SCHEMBL29888813 | 0.61 | CYP2D6 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445476-B2 | Carbacephem β-lactam antibiotics | ACHAOGEN, INC. (US) | 2013-05-21 | — | — | US | disclosed |
| WO-2010030811-A2 | CARBACEPHEM β-LACTAM ANTIBIOTICS | ACHAOGEN, INC. (US) | 2010-03-18 | — | — | WO | disclosed |