Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 1.00 |
| ▸ | ADRB1 | P08588 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | HTR7 | P34969 | 2/20 | 0.66 |
| ▸ | HTR1A | P08908 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526992 | 1.00 | SIRT6 (1.00) | SIRT6ADRB1MAPTHTR7HTR1A | |
| Hydrochloric Acid SCHEMBL1814630 | 0.98 | SIRT6 (0.96) | SIRT6ADRB1MAPTHTR7HTR1A | |
| Hydrogen Sulfide SCHEMBL28002215 | 0.98 | SIRT6 (0.96) | SIRT6ADRB1MAPTHTR7HTR1A | |
| SCHEMBL6152151 | 0.98 | SIRT6 (0.96) | SIRT6ADRB1MAPTHTR7HTR1A | |
| SCHEMBL6151805 | 0.98 | SIRT6 (0.96) | SIRT6ADRB1MAPTHTR7HTR1A | |
| SCHEMBL1496058 | 0.98 | SIRT6 (0.96) | SIRT6ADRB1MAPTHTR7HTR1A | |
| SCHEMBL27980887 | 0.95 | SIRT6 (0.90) | SIRT6ADRB1MAPTHTR7HTR1A | |
| SCHEMBL942183 | 0.93 | SIRT6 (0.87) | SIRT6ADRB1MAPTHTR7HTR1A | |
| Hydrochloric Acid SCHEMBL7984519 | 0.92 | SIRT6 (0.84) | SIRT6ADRB1MAPTHTR7HTR1A | |
| Propane SCHEMBL27412411 | 0.92 | SIRT6 (0.84) | SIRT6ADRB1MAPTHTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1777 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118666760-A | Nitrogen-heterocycle-containing alpha-carbonyl thioamide compound, and preparation method and application thereof | 浙大城市学院 | 2024-09-20 | — | — | CN | claimed |
| EP-3906235-B1 | METHOD FOR PREPARING SULFONAMIDES DRUGS | ASCENTAGE PHARMA SUZHOU CO LTD (CN) | 2023-03-15 | — | — | EP | claimed |
| US-11414400-B2 | Method for preparing sulfonamides drugs | ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) | 2022-08-16 | — | — | US | claimed |
| CN-112679445-B | Preparation method of posaconazole intermediate | 成都圣诺生物制药有限公司 | 2022-07-05 | — | — | CN | claimed |
| US-11261282-B2 | PEO-PPO-PEO triblock bipolymers, with amphoteric endings, as demulsifying agents for heavy crude oils | INSTITUTO MEXICANO DEL PETROLEO (MX) | 2022-03-01 | — | — | US | claimed |
| US-20210221788-A1 | METHOD FOR PREPARING SULFONAMIDES DRUGS | ASCENTAGE PHARMA GROUP CORP LIMITED (CN) | 2021-07-22 | — | — | US | claimed |
| CN-112679445-A | Preparation method of posaconazole intermediate | 成都圣诺生物制药有限公司 | 2021-04-20 | — | — | CN | claimed |
| CN-111410650-B | Process for the preparation of sulfonamides | 苏州亚盛药业有限公司 | 2020-12-08 | — | — | CN | claimed |
| US-20200347173-A1 | PEO-PPO-PEO TRIBLOCK BIPOLYMERS, WITH AMPHOTERIC ENDINGS, AS DEMULSIFYING AGENTS FOR HEAVY CRUDE OILS | INSTITUTO MEXICANO DEL PETROLEO (MX) | 2020-11-05 | — | — | US | claimed |
| CN-111410650-A | Process for the preparation of sulfonamides | 苏州亚盛药业有限公司 | 2020-07-14 | — | — | CN | claimed |
| EP-2135313-B1 | HIGH PERFORMANCE, HIGH DURABILITY NON-PRECIOUS METAL FUEL CELL CATALYSTS | 3M INNOVATIVE PROPERTIES CO (US) | 2011-09-14 | — | — | EP | claimed |
| EP-2135313-A1 | HIGH PERFORMANCE, HIGH DURABILITY NON-PRECIOUS METAL FUEL CELL CATALYSTS | 3M Innovative Properties Company (US) | 2009-12-23 | — | — | EP | claimed |
| WO-2008127828-A1 | HIGH PERFORMANCE, HIGH DURABILITY NON-PRECIOUS METAL FUEL CELL CATALYSTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-10-23 | — | — | WO | claimed |
| CN-1257896-C | Funcitonal molecule material containing four tertiary amine branches and preparation method | UNIV FUDAN (CN) | 2006-05-31 | — | — | CN | claimed |
| CN-1539833-A | Funcitonal molecule material containing four tertiary amine branches and preparation method | 复旦大学 | 2004-10-27 | — | — | CN | claimed |
| EP-0500050-B1 | Non-linear optical materials, method of manufacturing the same and optical wave length converter | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 1995-12-27 | — | — | EP | claimed |
| US-5460754-A | Non-linear optical material, method of manufacturing the same and optical wavelength converter | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1995-10-24 | — | — | US | claimed |
| US-5346653-A | Non-linear optical material, method of manufacturing the same and optical wavelength converter | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1994-09-13 | — | — | US | claimed |
| EP-0539180-A1 | Antiviral agents | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-04-28 | — | — | EP | claimed |
| EP-0500050-A2 | Non-linear optical materials, method of manufacturing the same and optical wave length converter | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1992-08-26 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11414400-B2 | Method for preparing sulfonamides drugs | BCL2, BCL3, BAK1 | SIRT6 766/4885ADRB1 3974/4885MAPT 4071/4885 |
| US-20210221788-A1 | METHOD FOR PREPARING SULFONAMIDES DRUGS | BCL2, BCL3, BAK1 | SIRT6 766/4885ADRB1 3974/4885MAPT 4071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.