Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.56 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13426255 | 0.89 | KCNH2 (0.57) | KCNH2TNIKPDGFRBKDRCHEK1 | |
| SCHEMBL13426245 | 0.89 | KCNH2 (0.60) | KCNH2KDRCHEK1MAPK1CLK4 | |
| SCHEMBL3396018 | 0.89 | KCNH2 (0.58) | KCNH2TNIKPDGFRBKDRMAPK1 | |
| SCHEMBL13426232 | 0.88 | KCNH2 (0.55) | KCNH2TNIKCHEK1CLK4ALDH1A1 | |
| SCHEMBL13425724 | 0.87 | KCNH2 (0.56) | KCNH2TNIKPDGFRBKDRMAPK1 | |
| SCHEMBL3427229 | 0.86 | KCNH2 (0.58) | KCNH2TNIKMAPK1CLK4ALDH1A1 | |
| SCHEMBL3434741 | 0.86 | KCNH2 (0.56) | KCNH2TNIKPDGFRBKDRCHEK1 | |
| SCHEMBL3394278 | 0.85 | KCNH2 (0.60) | KCNH2TNIKCHEK1MAPK1CLK4 | |
| SCHEMBL13425763 | 0.85 | KCNH2 (0.60) | KCNH2TNIKALDH1A1 | |
| SCHEMBL13425792 | 0.85 | KCNH2 (0.61) | KCNH2TNIKMAPK1CLK4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |