Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3399147 | 0.90 | KCNH2 (0.56) | KCNH2CLK4DYRK1ACHEK1USP2 | |
| SCHEMBL13425582 | 0.89 | KCNH2 (0.56) | KCNH2CLK4DYRK1ACHEK1USP2 | |
| SCHEMBL3362628 | 0.88 | KCNH2 (0.56) | KCNH2CLK4DYRK1ACHEK1ALDH1A1 | |
| SCHEMBL3398430 | 0.88 | KCNH2 (0.58) | KCNH2CLK4DYRK1ACHEK1USP2 | |
| SCHEMBL13426245 | 0.88 | KCNH2 (0.60) | KCNH2CLK4DYRK1ACHEK1USP2 | |
| SCHEMBL3397557 | 0.87 | KCNH2 (0.59) | KCNH2CLK4DYRK1AUSP2ALDH1A1 | |
| SCHEMBL13425837 | 0.86 | KCNH2 (0.54) | KCNH2CLK4DYRK1ACHEK1USP2 | |
| SCHEMBL3432595 | 0.85 | KCNH2 (0.54) | KCNH2CLK4DYRK1ACHEK1USP2 | |
| SCHEMBL13426280 | 0.84 | KCNH2 (0.58) | KCNH2CLK4CHEK1USP2ALDH1A1 | |
| SCHEMBL13425763 | 0.84 | KCNH2 (0.60) | KCNH2ALDH1A1MAPK14MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |