Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362817 | 0.81 | TOP2A (0.40) | PDE3BPDE3ATOP2A | |
| Hydrochloric Acid SCHEMBL3366759 | 0.81 | TOP2A (0.40) | PDE3BPDE3ATOP2A | |
| SCHEMBL21372291 | 0.75 | TOP2A (0.40) | PDE3BPDE3ATOP2A | |
| SCHEMBL13299225 | 0.75 | TOP2A (0.40) | PDE3BPDE3ATOP2A | |
| SCHEMBL13114364 | 0.73 | TOP2A (0.43) | TOP2A | |
| SCHEMBL3331529 | 0.70 | TOP2A (0.40) | TOP2A | |
| Hydrochloric Acid SCHEMBL3329341 | 0.69 | TOP2A (0.40) | TOP2A | |
| SCHEMBL335658 | 0.66 | TOP2A (0.38) | TOP2A | |
| SCHEMBL1433499 | 0.66 | TOP2A (0.38) | TOP2A | |
| SCHEMBL12746550 | 0.66 | TOP2A (0.36) | TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137196-B1 | TRICYCLIC NITROGEN CONTAINING COMPOUNDS AS ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2010-10-06 | — | — | EP | claimed |