Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.74 |
| ▸ | RXRB | P28702 | 2/20 | 0.74 |
| ▸ | RXRG | P48443 | 2/20 | 0.74 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.60 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CLK1 | P49759 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18169217 | 0.88 | RXRA (0.94) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL10247700 | 0.82 | RXRA (0.78) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL4327548 | 0.79 | HDAC1 (0.76) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL3045891 | 0.79 | HDAC1 (0.76) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL10247702 | 0.79 | HDAC1 (0.64) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL15427231 | 0.79 | NOTUM (0.64) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL15606558 | 0.78 | HDAC1 (0.70) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL6069881 | 0.78 | RXRA (0.76) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL13335161 | 0.78 | RXRA (0.68) | RXRARXRBRXRGHDAC3HDAC1 | |
| SCHEMBL3054236 | 0.77 | HDAC1 (0.72) | RXRARXRBRXRGHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |