Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | ROS1 | P08922 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4503767 | 0.78 | TDO2 (0.54) | CLK1ALOX5APFEN1 | |
| SCHEMBL3362961 | 0.77 | PIK3C3 (0.61) | PIK3C3DYRK1AALOX5APFEN1 | |
| SCHEMBL3383277 | 0.77 | MAPK14 (0.56) | NISCHMAPK14 | |
| SCHEMBL21859672 | 0.77 | ABL1 (0.62) | DYRK1ASCN9ANISCHMAPK13MAPK12 | |
| SCHEMBL319794 | 0.77 | NPC1 (0.50) | DYRK1ASCN9AALOX5APFEN1MAPK13 | |
| SCHEMBL30091450 | 0.77 | ABL1 (0.62) | DYRK1ASCN9ANISCHMAPK13MAPK12 | |
| SCHEMBL3360845 | 0.76 | EGLN2 (0.48) | PIK3C3DYRK1A | |
| SCHEMBL30507450 | 0.76 | DYRK1A (0.53) | DYRK1AALOX5APFEN1 | |
| SCHEMBL2371385 | 0.76 | DYRK1A (0.53) | DYRK1AALOX5APFEN1 | |
| SCHEMBL21001790 | 0.74 | DYRK1A (0.59) | DYRK1AADORA2BMAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |