Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.70 |
| ▸ | MAOB | P27338 | 1/20 | 0.70 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803477 | 0.83 | MAOA (0.54) | MAOAMAOBPTGS2HPGDLMNA | |
| SCHEMBL12320662 | 0.83 | MAOA (0.54) | MAOAMAOBPTGS2HPGDLMNA | |
| SCHEMBL4664485 | 0.83 | MAOA (0.54) | MAOAMAOBPTGS2HPGDLMNA | |
| Iproniazid SCHEMBL4153 | 0.82 | MAOA (1.00) | MAOAMAOBPTGS2HPGDLMNA | |
| Iproniazid SCHEMBL3597361 | 0.81 | MAOA (0.96) | MAOAMAOBPTGS2HPGDLMNA | |
| Iproniazid SCHEMBL3001881 | 0.81 | MAOA (0.96) | MAOAMAOBPTGS2HPGDLMNA | |
| Iproniazid SCHEMBL158555 | 0.78 | HPGD (1.00) | MAOAMAOBPTGS2HPGDLMNA | |
| SCHEMBL2989617 | 0.78 | MAOA (0.67) | MAOAMAOBPTGS2HPGDLMNA | |
| Iproniazid SCHEMBL15200763 | 0.77 | HPGD (1.00) | MAOAMAOBPTGS2HPGDLMNA | |
| SCHEMBL3001440 | 0.77 | MAOA (0.70) | MAOAMAOBPTGS2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010037134-A2 | MULTI-STAGE STEM CELL CARCINOGENESIS | STEMLIFELINE, INC. (US) | 2010-04-01 | — | — | WO | disclosed |