Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL190954 | 0.76 | AURKA (0.63) | AURKAHSP90AA1PRKACAADORA2AGABRA1 | |
| SCHEMBL29620532 | 0.76 | AURKA (0.63) | AURKAHSP90AA1PRKACAADORA2AGABRA1 | |
| SCHEMBL29736136 | 0.74 | AURKA (0.61) | AURKAHSP90AA1PRKACAADORA2AGABRA1 | |
| Ammonia Solution, Strong SCHEMBL20267253 | 0.74 | AURKA (0.61) | AURKAHSP90AA1PRKACAADORA2AGABRA1 | |
| SCHEMBL18732403 | 0.72 | KMT2A (0.61) | AURKAHSP90AA1PRKACAADORA2AGABRA1 | |
| SCHEMBL21003801 | 0.72 | KMT2A (0.61) | AURKAHSP90AA1PRKACAADORA2AGABRA1 | |
| SCHEMBL29730468 | 0.72 | KMT2A (0.61) | AURKAHSP90AA1PRKACAADORA2AGABRA1 | |
| SCHEMBL18731741 | 0.72 | KMT2A (0.61) | AURKAHSP90AA1PRKACAADORA2AGABRA1 | |
| Ethylene SCHEMBL28961184 | 0.72 | AURKA (0.59) | AURKAHSP90AA1PRKACAADORA2AGABRA1 | |
| SCHEMBL18212429 | 0.71 | KMT2A (0.59) | AURKAHSP90AA1PRKACAADORA2AGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144672-A1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | BAYER CROPSCIENCE AG (DE) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144672-A1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | PIR, ITPA, DDT | AURKA 2902/4885HSP90AA1 2432/4885PRKACA 569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.