SCHEMBL3363131

SCHEMBL3363131

O=C(OCC(F)(F)C(F)(F)COC(=O)c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.58
ESR2 Q92731 3/20 0.58
CA12 O43570 2/20 0.58
CA1 P00915 2/20 0.58
CA2 P00918 2/20 0.58
CA7 P43166 2/20 0.58
CA9 Q16790 2/20 0.58
CA14 Q9ULX7 2/20 0.58
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
TSHR P16473 3/20 0.55
ALDH1A1 P00352 2/20 0.55
CHRM1 P11229 1/20 0.55
SLC6A2 P23975 1/20 0.55
KDR P35968 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
MAPK1 P28482 3/20 0.54
LMNA P02545 3/20 0.53
CYP1A2 P05177 1/20 0.51
CYP2D6 P10635 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3360500 0.93 ESR1 (0.55) ESR1ESR2CA12CA1CA2
SCHEMBL9142594 0.90 ESR1 (0.51) ESR1ESR2CA12CA1CA2
SCHEMBL7945129 0.89 ESR1 (0.58) ESR1ESR2CA12CA1CA2
SCHEMBL9578640 0.87 ESR1 (0.49) ESR1ESR2CA12CA1CA2
SCHEMBL24305987 0.85 MAPK1 (0.60) ESR1ESR2CA12CA1CA2
SCHEMBL1348236 0.84 MAPK1 (0.68) ESR1ESR2CA12CA1CA2
SCHEMBL24361312 0.84 ESR1 (0.53) ESR1ESR2CA12CA1CA2
SCHEMBL24628483 0.84 LMNA (0.58) ESR1ESR2CA12CA1CA2
SCHEMBL21185910 0.83 TDP1 (0.52) ESR1ESR2CA12CA1CA2
SCHEMBL25563707 0.82 ESR1 (0.51) ESR1ESR2CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7691931-B2 Organic-inorganic hybrid material and method of preparing the organic-inorganic hybrid material, and electrophotographic photoreceptor, process cartridge, image forming apparatus and image forming method using the organic-inorganic hybrid material RICOH COMPANY LTD. (JP) 2010-04-06 US disclosed
US-7122284-B2 Electrophotographic photoconductor, image forming method and apparatus, and process cartridge using the photoconductor, and long-chain alkyl group containing bisphenol compound and polymer made therefrom RICOH COMPANY, LTD. (JP) 2006-10-17 US disclosed
US-7071285-B2 Aromatic polycarbonate resin, electrophotographic photoconductor, process cartridge, and electrophotographic image forming method and apparatus RICOH COMPANY, LTD. (JP) 2006-07-04 US disclosed
US-20060122303-A1 Organic-inorganic hybrid material and method of preparing the organic-inorganic hybrid material, and electrophotographic photoreceptor, process cartridge, image forming apparatus and image forming method using the organic-inorganic hybrid material RICOH COMPANY, LTD. (JP) 2006-06-08 US disclosed
US-7056633-B2 Electrophotographic photoconductor, image forming method and apparatus, and process cartidge using the photocondutor, and long-chain alkyl group containing bisphenol compound and polymer made therefrom RICOH COMPANY, LTD. (JP) 2006-06-06 US disclosed
US-6939651-B2 Electrophotographic photoconductor, and process cartridge and electrophotographic apparatus using the same RICOH COMPANY, LTD. (JP) 2005-09-06 US disclosed
US-6919419-B2 AROMATIC BLOCK POLYCARBONATE RESIN, DIPHENOL COMPOUND FOR PREPARATION OF THE POLYCARBONATE RESIN, ELECTRO-PHOTOGRAPHIC PHOTOCONDUCTOR, ELECTRO-PHOTOGRAPHIC IMAGE FORMING APPARATUS AND PROCESS, AND PROCESS CARTRIDGE RICOH COMPANY LTD. (JP) 2005-07-19 US disclosed
US-20050003287-A1 Aromatic polycarbonate resin, electrophotographic photoconductor, process cartridge, and electrophotographic image forming method and apparatus RICOH COMPANY, LTD. (JP) 2005-01-06 US disclosed
US-6790571-B2 FORMED FROM N-(4-(2,2-BIS(4-HYDROXYPHENYL)VINYL)PHENYL)-N,N BIS(4-TOLYL)AMINE; IMPROVED DURABILITY; FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICE RICOH COMPANY, LTD. (JP) 2004-09-14 US disclosed
US-20040002574-A1 Aromatic block polycarbonate resin, diphenol compound for preparation of the polycarbonate resin, electro-photographic photoconductor, electro-photographic image forming apparatus and process, and process cartridge RICOH COMPANY, LTD. (JP) 2004-01-01 US disclosed
US-20030198881-A1 Electrophotographic photoconductor, image forming method and apparatus, and process cartridge using the photoconductor, and long-chain alkyl group containing bisphenol compound and polymer made therefrom RICOH COMPANY, LTD. (JP) 2003-10-23 US disclosed
US-6576386-B1 AROMATIC BLOCK POLYCARBONATE RESIN, DIPHENOL COMPOUND FOR PREPARATION OF THE POLYCARBONATE RESIN, ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS AND PROCESS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2003-06-10 US disclosed
US-6548216-B2 Forming electrostatic latent images RICOH COMPANY, LTD. (JP) 2003-04-15 US disclosed
US-20030059695-A1 Electrophotographic photoconductor, and process cartridge and electrophotographic apparatus using the same RICOH COMPANY, LTD. (JP) 2003-03-27 US disclosed
US-6486293-B1 Electrophotographic photoconductor and method of producing aromatic polycarbonate resin for use in the photoconductor RICOH COMPANY, LTD. (JP) 2002-11-26 US disclosed
US-6444387-B2 USED FOR SURFACE LAYER OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR, INTERMEDIATE TRANSFER MEDIUM, AND THE LIKE IMAGE BEARING MEMBERS TO IMPROVE ABRASION RESISTANCE THEREOF RICOH COMPANY LIMITED (JP) 2002-09-03 US disclosed
US-20020098430-A1 Aromatic polycarbonate resin, electrophotographic photoconductor, process cartridge, and electrophotographic image forming method and apparatus RICOH COMPANY, LTD. (JP) 2002-07-25 US disclosed
US-20020025483-A1 Electrophotographic photoconductor, image forming method and apparatus, and process cartridge using the photoconductor, and long-chain alkyl group containing bisphenol compound and polymer made therefrom RICOH COMPANY, LTD. (JP) 2002-02-28 US disclosed
US-20010012594-A1 Image bearing material, electrophotographic photoreceptor using the image bearing material, and image forming apparatus using the photoreceptor RICOH COMPANY LIMITED (JP) 2001-08-09 US disclosed