Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | TAS2R46 | P59540 | 4/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336313 | 1.00 | LMNA (0.57) | LMNAALOX15CYP1B1ALDH1A1MEN1 | |
| SCHEMBL1245213 | 0.93 | LMNA (0.65) | LMNAALOX15CYP1B1ALDH1A1MEN1 | |
| SCHEMBL20608601 | 0.93 | LMNA (0.65) | LMNAALOX15CYP1B1ALDH1A1MEN1 | |
| SCHEMBL20610540 | 0.93 | LMNA (0.65) | LMNAALOX15CYP1B1ALDH1A1MEN1 | |
| SCHEMBL23360385 | 0.81 | LMNA (0.86) | LMNAALOX15CYP1B1ALDH1A1MEN1 | |
| Cembrene_A SCHEMBL2041140 | 0.81 | LMNA (0.86) | LMNAALOX15CYP1B1ALDH1A1MEN1 | |
| Cembrene_A SCHEMBL11402150 | 0.81 | LMNA (0.86) | LMNAALOX15CYP1B1ALDH1A1MEN1 | |
| SCHEMBL31091157 | 0.81 | LMNA (0.86) | LMNAALOX15CYP1B1ALDH1A1MEN1 | |
| SCHEMBL23360384 | 0.81 | LMNA (0.86) | LMNAALOX15CYP1B1ALDH1A1MEN1 | |
| SCHEMBL31509123 | 0.81 | LMNA (0.86) | LMNAALOX15CYP1B1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230323314-A1 | INCREASING PRODUCTIVITY OF E. COLI HOST CELLS THAT FUNCTIONALLY EXPRESS P450 ENZYMES | SYMBIOTIC CAPITAL AGENCY LLC, AS ADMINISTRATIVE AND COLLATERAL AGENT | 2023-10-12 | — | — | US | disclosed |
| EP-3337893-B1 | INCREASING PRODUCTIVITY OF E. COLI HOST CELLS THAT FUNCTIONALLY EXPRESS P450 ENZYMES | MANUS BIO INC (US) | 2023-07-19 | — | — | EP | disclosed |
| US-20230180691-A1 | SECONDARY METABOLITE SCREENING SYSTEM | MANUS BIO INC. | 2023-06-15 | — | — | US | disclosed |
| EP-3183357-B1 | METHOD FOR PRODUCING OXYGENATED VALENCENE | MANUS BIO INC (US) | 2020-03-04 | — | — | EP | disclosed |
| US-20190270971-A1 | INCREASING PRODUCTIVITY OF MICROBIAL HOST CELLS THAT FUNCTIONALLY EXPRESS P450 ENZYMES | MANUS BIO INC. | 2019-09-05 | — | — | US | disclosed |
| US-9856460-B2 | Nucleic acids encoding synthetic scaffolds and host cells genetically modified with the nucleic acids | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-01-02 | — | — | US | disclosed |
| EP-2489672-B1 | Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof | UNIV CALIFORNIA (US) | 2017-01-18 | — | — | EP | disclosed |
| US-20140370595-A1 | Use of Synthetic Scaffolds for the Production of Biosynthetic Pathway Products | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2014-12-18 | — | — | US | disclosed |
| US-8765403-B2 | Use of synthetic scaffolds for the production of biosynthetic pathway products | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-07-01 | — | — | US | disclosed |
| US-8759632-B2 | Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-06-24 | — | — | US | disclosed |
| US-8097438-B2 | Nucleic acids encoding modified cytochrome P450 enzymes and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-01-17 | — | — | US | disclosed |
| US-20110008829-A1 | Use of Synthetic Scaffolds for the Production of Biosynthetic Pathway Products | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2011-01-13 | — | — | US | disclosed |
| US-20100218283-A1 | POLYNUCLEOTIDES ENCODING ISOPRENOID MODIFYING ENZYMES AND METHODS OF USE THEREOF | EUAGORE, LLC | 2010-08-26 | — | — | US | disclosed |
| US-20090098626-A1 | NUCLEIC ACIDS ENCODING MODIFIED CYTOCHROME P450 ENZYMES AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-16 | — | — | US | disclosed |
| US-20080233623-A1 | GENETICALLY MODIFIED HOST CELLS FOR INCREASED P450 ACTIVITY LEVELS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-09-25 | — | — | US | disclosed |
| US-20080124772-A1 | Plant enzymes for bioconversion | PLANT RESEARCH INTERNATIONAL B.V. | 2008-05-29 | — | — | US | disclosed |
| EP-1916307-A1 | Plant enzymes for bioconversion | Plant Research International B.V. (NL) | 2008-04-30 | — | — | EP | disclosed |
| US-20070300327-A1 | Plant enzymes for bioconversion | PLANT RESEARCH INTERNATIONAL B.V. | 2007-12-27 | — | — | US | disclosed |
| US-7214507-B2 | Plant enzymes for bioconversion | PLANT RESEARCH INTERNATIONAL B.V. (NL) | 2007-05-08 | — | — | US | disclosed |
| US-20050019882-A1 | Using plant enzymes for the production of flavor, fragrance, pharmaceutical or bio-control agents from less valuable substrates; terpenoid biosynthesis | STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK (NL) | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080124772-A1 | Plant enzymes for bioconversion | STS, SQLE, CYP51A1 | LMNA 2821/4885ALOX15 545/4885CYP1B1 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.