Fluorescein

Fluorescein

SCHEMBL336329

CCC(=O)O.CCC(=O)O.O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2ccccc21

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 10/20 0.81
MAPT P10636 4/20 0.81
MEN1 O00255 3/20 0.81
KMT2A Q03164 3/20 0.81
HTT P42858 2/20 0.81
HPGD P15428 2/20 0.81
TDP1 Q9NUW8 2/20 0.81
CYP2C19 P33261 1/20 0.81
RECQL P46063 1/20 0.81
BLM P54132 1/20 0.81
SMAD3 P84022 1/20 0.81
PRMT1 Q99873 1/20 0.81
ACE2 Q9BYF1 1/20 0.81
LMNA P02545 3/20 0.61
ALOX12 P18054 2/20 0.61
GPR55 Q9Y2T6 2/20 0.61
POLB P06746 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
CYP3A4 P08684 2/20 0.60
ALDH1A1 P00352 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorescein SCHEMBL21043898 1.00 FTO (0.81) FTOMAPTMEN1KMT2AHTT
Fluorescein SCHEMBL10388070 0.92 FTO (0.75) FTOMAPTMEN1KMT2AHTT
Fluorescein SCHEMBL27395251 0.91 FTO (0.82) FTOMAPTMEN1KMT2AHTT
Fluorescein SCHEMBL27504008 0.91 FTO (0.82) FTOMAPTMEN1KMT2AHTT
Fluorescein SCHEMBL531261 0.91 FTO (0.87) FTOMAPTMEN1KMT2AHTT
Fluorescein SCHEMBL4235133 0.91 FTO (0.87) FTOMAPTMEN1KMT2AHTT
Fluorescein SCHEMBL2361033 0.91 FTO (0.87) FTOMAPTMEN1KMT2AHTT
Fluorescein SCHEMBL20239317 0.91 FTO (0.87) FTOMAPTMEN1KMT2AHTT
Fluorescein SCHEMBL27157739 0.91 FTO (0.92) FTOMAPTMEN1KMT2AHTT
Fluorescein SCHEMBL8462127 0.91 FTO (0.97) FTOMAPTMEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8097404-B2 Composition and method for cell permeabilization comprising N-octyl-β-D-glucopyranoside, sodium polyphosphates, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORPORATION (US) 2012-01-17 US claimed
EP-2107119-B1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORP (US) 2010-05-12 EP claimed
EP-2107119-A1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane Millipore Corporation (US) 2009-10-07 EP claimed
CN-101551333-A Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORP (US) 2009-10-07 CN claimed
US-20090246822-A1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane EMD MILLIPORE CORPORATION 2009-10-01 US claimed
US-11519014-B2 Specific substrate of an ALDH isoenzyme ADVANCED BIODESIGN (FR) 2022-12-06 US disclosed
US-20190233871-A1 SPECIFIC SUBSTRATE OF AN ALDH ISOENZYME ADVANCED BIODESIGN (FR) 2019-08-01 US disclosed
US-8097404-B2 Composition and method for cell permeabilization comprising N-octyl-β-D-glucopyranoside, sodium polyphosphates, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORPORATION (US) 2012-01-17 US disclosed
EP-2107119-B1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORP (US) 2010-05-12 EP disclosed
EP-2126122-A1 METHOD AND TEST KIT FOR DETERMINING THE AMOUNTS OF TARGET SEQUENCES AND NUCLEOTIDE VARIATIONS THEREIN Valtion Teknillinen Tutkimuskeskus (FI) 2009-12-02 EP disclosed
EP-2107119-A1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane Millipore Corporation (US) 2009-10-07 EP disclosed
CN-101551333-A Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORP (US) 2009-10-07 CN disclosed
US-20090246822-A1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane EMD MILLIPORE CORPORATION 2009-10-01 US disclosed
US-20090011944-A1 METHOD AND TEST KIT FOR DETECTING NUCLEOTIDE VARIATIONS VALTION TEKNILLINEN TUTKIMUSKEKUS (FI) 2009-01-08 US disclosed
WO-2008102057-A9 METHOD AND TEST KIT FOR DETERMINING THE AMOUNTS OF TARGET SEQUENCES AND NUCLEOTIDE VARIATIONS THEREIN VALTION TEKNILLINEN (FI) 2008-10-09 WO disclosed
WO-2008102057-A1 METHOD AND TEST KIT FOR DETERMINING THE AMOUNTS OF TARGET SEQUENCES AND NUCLEOTIDE VARIATIONS THEREIN VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) 2008-08-28 WO disclosed