Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.54 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.44 |
| ▸ | VNN1 | O95497 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3399312 | 0.85 | CLK4 (0.57) | CLK4DYRK1APDE5AMAPK13MAPK12 | |
| SCHEMBL439371 | 0.82 | CLK4 (0.66) | CLK4DYRK1APDE5AVNN1KDM4E | |
| SCHEMBL3397266 | 0.78 | CLK4 (0.56) | CLK4DYRK1APDE5AMAPK13MAPK12 | |
| SCHEMBL13426135 | 0.77 | KCNH2 (0.45) | MAPK14KCNH2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL2311658 | 0.76 | PDE5A (0.50) | CLK4DYRK1APDE5AVNN1TP53 | |
| SCHEMBL13425540 | 0.76 | KCNH2 (0.51) | CLK4MAPK14KCNH2KDM4EALDH1A1 | |
| SCHEMBL13426697 | 0.76 | KCNH2 (0.54) | CLK4KCNH2GSK3BKDM4EALDH1A1 | |
| SCHEMBL13426790 | 0.74 | KCNH2 (0.57) | CLK4DYRK1AKCNH2VNN1KDM4E | |
| SCHEMBL13426213 | 0.74 | KCNH2 (0.56) | CLK4KCNH2ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL13426229 | 0.74 | KCNH2 (0.56) | CLK4DYRK1AMAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |