Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 7/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.56 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.45 |
| ▸ | VNN1 | O95497 | 2/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439371 | 0.84 | CLK4 (0.66) | CLK4DYRK1ACLK1VNN1PDE5A | |
| SCHEMBL3399312 | 0.83 | CLK4 (0.57) | CLK4DYRK1ACLK1MAPK13MAPK12 | |
| SCHEMBL3363498 | 0.78 | CLK4 (0.54) | CLK4DYRK1ACLK1MAPK13MAPK12 | |
| SCHEMBL953773 | 0.76 | TSHR (0.56) | CLK4DYRK1ACLK1VNN1PDE5A | |
| SCHEMBL8422251 | 0.75 | MEN1 (0.68) | CLK4DYRK1ACLK1 | |
| SCHEMBL13425582 | 0.75 | KCNH2 (0.56) | CLK4DYRK1AMAPK13MAPK12MAPK11 | |
| SCHEMBL13426113 | 0.74 | KCNH2 (0.54) | CLK4DYRK1AMAPK14KCNH2TSHR | |
| SCHEMBL20489508 | 0.74 | CLK4 (0.48) | CLK4DYRK1ACLK1VNN1PDE5A | |
| SCHEMBL20489546 | 0.74 | CLK4 (0.48) | CLK4DYRK1ACLK1VNN1PDE5A | |
| SCHEMBL22122521 | 0.73 | PDE5A (0.56) | CLK4DYRK1AVNN1PDE5ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |