SCHEMBL3363601

SCHEMBL3363601

COC(=O)c1cc(NC(C)=O)ccc1O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.76
CDK1 P06493 1/20 0.65
CA12 O43570 1/20 0.61
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
CA7 P43166 1/20 0.61
CA9 Q16790 1/20 0.61
CA14 Q9ULX7 1/20 0.61
KMT2A Q03164 3/20 0.58
MEN1 O00255 2/20 0.58
NPC1 O15118 1/20 0.58
RAB9A P51151 1/20 0.58
TDP1 Q9NUW8 1/20 0.57
EPHX2 P34913 1/20 0.56
EGFR P00533 3/20 0.55
NOX4 Q9NPH5 1/20 0.55
MAOB P27338 1/20 0.54
MAPT P10636 1/20 0.53
PTPN11 Q06124 1/20 0.52
POLB P06746 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2127575 0.86 SMN1; SMN2 (1.00) SMN1; SMN2CDK1CA12CA1CA2
SCHEMBL8137802 0.86 SMN1; SMN2 (0.75) SMN1; SMN2CDK1CA12CA1CA2
SCHEMBL10334067 0.84 KMT2A (0.71) SMN1; SMN2CDK1CA12CA1CA2
SCHEMBL22200953 0.84 SMN1; SMN2 (0.55) SMN1; SMN2CDK1CA12CA1CA2
SCHEMBL30621955 0.84 SMN1; SMN2 (0.57) SMN1; SMN2CDK1CA12CA1CA2
SCHEMBL925741 0.84 SMN1; SMN2 (0.57) SMN1; SMN2CDK1CA12CA1CA2
SCHEMBL23796819 0.83 SMN1; SMN2 (0.58) SMN1; SMN2CA12CA1CA2CA7
SCHEMBL30031490 0.83 SMN1; SMN2 (0.58) SMN1; SMN2CA12CA1CA2CA7
SCHEMBL18737818 0.83 SMN1; SMN2 (0.66) SMN1; SMN2CDK1KMT2AMEN1RAB9A
SCHEMBL170522 0.82 KDM4C (0.62) SMN1; SMN2CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9929348-B2 Organic semiconductor composition comprising organic semiconductor material and polymer compound FUJIFILM CORPORATION (JP) 2018-03-27 US disclosed
US-20160064674-A1 ORGANIC SEMICONDUCTOR COMOSITION, ORGANIC THIN-FILM TRANSISTOR, ELECTRONIC PAPER, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-03-03 US disclosed
US-20160064674-A1 ORGANIC SEMICONDUCTOR COMOSITION, ORGANIC THIN-FILM TRANSISTOR, ELECTRONIC PAPER, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-03-03 US disclosed
US-9224518-B2 Conductive composition, conductive member, conductive member production method, touch panel, and solar cell FUJIFILM CORPORATION (JP) 2015-12-29 US disclosed
US-9224518-B2 Conductive composition, conductive member, conductive member production method, touch panel, and solar cell FUJIFILM CORPORATION (JP) 2015-12-29 US disclosed
WO-2010042600-A2 PHOTO-ACTIVATABLE THERAPEUTIC AGENTS AND METHODS OF USING THE UAB RESEARCH FOUNDATION (US) 2010-04-15 WO disclosed
WO-2010042600-A2 PHOTO-ACTIVATABLE THERAPEUTIC AGENTS AND METHODS OF USING THE UAB RESEARCH FOUNDATION (US) 2010-04-15 WO disclosed
US-4933330-A PSORIASIS DAK-LABORATORIET (DK) 1990-06-12 US disclosed
EP-0291159-A2 Aminosalicylic-acid derivatives for the treatment of psoriasis DAK-LABORATORIET A/S (DK) 1988-11-17 EP disclosed
US-4409232-A HYPOTENSIVE AGENTS, ANTIARRHYTHMIA AGENTS BEIERSDORF AKTIENGESELLSCHAFT (DE) 1983-10-11 US disclosed
EP-0045955-B1 ALKYL AND CYCLOALKYL SUBSTITUTED 2-(2-(2-HYDROXY-3-TERT.-BUTYLAMINO-PROPOXY)-5-ACYLAMINOPHENYL)-1,3,4-OXADIAZOLES, THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM Beiersdorf Aktiengesellschaft (DE) 1983-08-31 EP disclosed
EP-0045955-A1 Alkyl and cycloalkyl substituted 2-(2-(2-hydroxy-3-tert.-butylamino-propoxy)-5-acylaminophenyl)-1,3,4-oxadiazoles, their preparation and pharmaceutical preparations containing them Beiersdorf Aktiengesellschaft (DE) 1982-02-17 EP disclosed