SCHEMBL3363768

SCHEMBL3363768

CCC(O)(c1ccc(OC(F)(F)F)cc1)c1cnc(C)nc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CCR6 P51684 5/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ POLB P06746 1/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ PPARD Q03181 2/20 0.37
▸ KCNH2 Q12809 4/20 0.37
▸ SCN10A Q9Y5Y9 2/20 0.37
▸ GABBR2 O75899 1/20 0.37
▸ GABBR1 Q9UBS5 1/20 0.37
▸ SIGMAR1 Q99720 1/20 0.37
▸ HRH1 P35367 1/20 0.37
▸ FNTB P49356 1/20 0.37
▸ LMNA P02545 1/20 0.37
▸ HDAC3 O15379 1/20 0.36
▸ HDAC1 Q13547 1/20 0.36
▸ HDAC2 Q92769 1/20 0.36
▸ NOS3 P29474 1/20 0.36
▸ NOS1 P29475 1/20 0.36
▸ NOS2 P35228 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11730843 0.78 CYP3A4 (0.47) CCR6KCNH2
SCHEMBL11440163 0.73 CYP19A1 (0.40) CCR6KCNH2
SCHEMBL11431959 0.73 CCR6 (0.42) CCR6KCNH2SIGMAR1HRH1FNTB
SCHEMBL16215338 0.72 GABBR2 (0.49) KCNH2SCN10AGABBR2GABBR1
SCHEMBL17172180 0.70 CCR6 (0.38) CCR6L3MBTL1KCNH2
SCHEMBL17157316 0.70 CYP3A4 (0.45) CCR6SCN10A
SCHEMBL20596700 0.70 CYP3A4 (0.45) CCR6SCN10A
SCHEMBL12777855 0.70 GABBR2 (0.39) L3MBTL1POLBMEN1KMT2AKCNH2
SCHEMBL11433758 0.69 HDAC3 (0.41) CCR6KCNH2SIGMAR1HRH1FNTB
SCHEMBL17172224 0.69 CYP3A4 (0.39) KCNH2SCN10AGABBR2GABBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2274979-B1 AGENT FOR IMPROVING LAWN GRASS QUALITIES COSMO ALA CO LTD (JP) 2016-08-24 — — EP disclosed
US-8916502-B2 Agent for improving lawn grass qualities COSMO OIL CO., LTD. (JP) 2014-12-23 — — US disclosed
US-8889594-B2 Agent for improving good rice seedling growth COSMO OIL CO., LTD. (JP) 2014-11-18 — — US disclosed
US-20100331183-A1 AGENT FOR IMPROVING GOOD RICE SEEDLING GROWTH COSMO OIL CO., LTD (JP) 2010-12-30 — — US disclosed
US-20100317527-A1 AGENT FOR IMPROVING LAWN GRASS QUALITIES COSMO OIL CO., LTD. (JP) 2010-12-16 — — US disclosed
US-20100234231-A1 YIELD ENHANCING AGENT FOR HARVESTING PART OF CROP COSMO OIL CO., LTD. (JP) 2010-09-16 — — US disclosed
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