Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | VEGFA | P15692 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5728291 | 0.83 | EPAS1 (0.45) | TRPV4SLC22A12PDE4APDE4CPDE4D | |
| SCHEMBL31245789 | 0.83 | SLC22A12 (0.41) | TRPV4SLC22A12PDE4APDE4CPDE4D | |
| SCHEMBL21723413 | 0.83 | SLC22A12 (0.41) | TRPV4SLC22A12PDE4APDE4CPDE4D | |
| SCHEMBL1738137 | 0.82 | TRPV4 (0.54) | TRPV4SLC22A12MRGPRX4PDE4APDE4C | |
| SCHEMBL16179448 | 0.82 | MRGPRX4 (0.42) | ARTRPV4MRGPRX4PDE4APDE4C | |
| SCHEMBL1398164 | 0.81 | AR (0.48) | ARTRPV4PDE4APDE4CPDE4D | |
| SCHEMBL1411551 | 0.79 | PTGS1 (0.46) | MRGPRX4EPAS1 | |
| SCHEMBL16962986 | 0.78 | PTGDR2 (0.41) | TRPV4HSD11B1PDE4APDE4CPDE4D | |
| SCHEMBL27825202 | 0.78 | EPAS1 (0.43) | SLC22A12HSD11B1EPAS1 | |
| SCHEMBL6700942 | 0.77 | PDE4A (0.42) | TRPV4HSD11B1PDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |