Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | PGAM1 | P18669 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | GNG2 | P59768 | 3/20 | 0.37 |
| ▸ | GNB1 | P62873 | 3/20 | 0.37 |
| ▸ | CHAT | P28329 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3363866 | 1.00 | CYP1A2 (0.59) | CYP1A2MAPK1CYP2C19HIF1AHSD17B10 | |
| SCHEMBL13496251 | 1.00 | CYP1A2 (0.59) | CYP1A2MAPK1CYP2C19HIF1AHSD17B10 | |
| SCHEMBL3363100 | 0.93 | HIF1A (0.52) | CYP1A2MAPK1CYP2C19HIF1AHSD17B10 | |
| SCHEMBL3363102 | 0.93 | HIF1A (0.52) | CYP1A2MAPK1CYP2C19HIF1AHSD17B10 | |
| SCHEMBL3364259 | 0.90 | MAPK1 (0.52) | CYP1A2MAPK1CYP2C19HIF1AHSD17B10 | |
| SCHEMBL13496261 | 0.90 | MAPK1 (0.52) | CYP1A2MAPK1CYP2C19HIF1AHSD17B10 | |
| SCHEMBL3364255 | 0.90 | MAPK1 (0.52) | CYP1A2MAPK1CYP2C19HIF1AHSD17B10 | |
| SCHEMBL3363626 | 0.90 | HIF1A (0.47) | CYP1A2MAPK1CYP2C19HIF1AHSD17B10 | |
| SCHEMBL3363622 | 0.90 | HIF1A (0.47) | CYP1A2MAPK1CYP2C19HIF1AHSD17B10 | |
| SCHEMBL3366765 | 0.82 | GNG2 (0.48) | CYP1A2MAPK1CYP2C19HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100031452-A1 | AZO DYES | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2010-02-11 | — | — | US | disclosed |
| WO-2010003969-A2 | NEW AZO DYES | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2010-01-14 | — | — | WO | disclosed |
| WO-2010003969-A2 | NEW AZO DYES | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2010-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100031452-A1 | AZO DYES | IK, H1-10, RB1 | CYP1A2 217/4885MAPK1 1638/4885CYP2C19 367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.