Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | CCR3 | P51677 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3365081 | 0.99 | DPP4 (0.52) | DPP4MEN1KMT2ACCR3CYP2C9 | |
| SCHEMBL3360363 | 0.84 | CCR3 (0.44) | MEN1KMT2ACCR3CYP2C9CYP2C19 | |
| SCHEMBL3365200 | 0.79 | DPP4 (0.53) | DPP4MEN1KMT2AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL3362385 | 0.78 | DPP4 (0.54) | DPP4MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL3362127 | 0.74 | DPP4 (0.60) | DPP4MAPK1 | |
| Hydrochloric Acid SCHEMBL3361829 | 0.73 | DPP4 (0.61) | DPP4MAPK1 | |
| SCHEMBL3361000 | 0.72 | DPP4 (0.61) | DPP4MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3362995 | 0.72 | DPP4 (0.61) | DPP4MEN1KMT2AALDH1A1 | |
| SCHEMBL23682656 | 0.70 | TACR3 (0.83) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL7362106 | 0.69 | ALDH1A1 (0.64) | MEN1KMT2ACYP2C9CYP2C19MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | claimed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |