SCHEMBL3363997

SCHEMBL3363997

[CH2]C1CCCCN1C(=O)c1nc(C2CC2)sc1-c1cccc(Cl)c1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 20/20 0.49
HCRTR2 O43614 20/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3364004 0.88 HCRTR1 (0.51) HCRTR1HCRTR2
SCHEMBL3047100 0.87 HCRTR1 (0.47) HCRTR1HCRTR2
SCHEMBL3361871 0.86 HCRTR1 (0.48) HCRTR1HCRTR2
SCHEMBL3047103 0.86 HCRTR1 (0.53) HCRTR1HCRTR2
Hydrochloric Acid SCHEMBL3043151 0.85 HCRTR1 (0.52) HCRTR1HCRTR2
Hydrochloric Acid SCHEMBL3043159 0.85 HCRTR1 (0.52) HCRTR1HCRTR2
SCHEMBL3363286 0.82 HCRTR1 (0.53) HCRTR1HCRTR2
SCHEMBL3048825 0.81 HCRTR1 (0.43) HCRTR1HCRTR2
SCHEMBL3048807 0.81 HCRTR1 (0.48) HCRTR1HCRTR2
SCHEMBL3048804 0.81 HCRTR1 (0.48) HCRTR1HCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2155739-B1 2-CYCLOPROPYL-THIAZOLE DERIVATIVES ACTELION PHARMACEUTICALS LTD (CH) 2010-10-06 EP disclosed