Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361876 | 0.89 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL3056082 | 0.87 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL3050233 | 0.86 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL3053095 | 0.86 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL3053091 | 0.86 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL3363997 | 0.86 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL3363286 | 0.81 | HCRTR1 (0.53) | HCRTR1HCRTR2 | |
| SCHEMBL3361281 | 0.80 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL3361276 | 0.80 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL924043 | 0.80 | ALDH1A1 (0.48) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155739-B1 | 2-CYCLOPROPYL-THIAZOLE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-10-06 | — | — | EP | claimed |
| EP-2155739-B1 | 2-CYCLOPROPYL-THIAZOLE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-10-06 | — | — | EP | disclosed |