Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 8/20 | 0.55 |
| ▸ | BCHE | P06276 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL29462685 | 1.00 | ACHE (0.55) | ACHEBCHEKDM4EMEN1RGS12 | |
| SCHEMBL307903 | 0.97 | ACHE (0.53) | ACHEBCHE | |
| SCHEMBL29752612 | 0.97 | ACHE (0.53) | ACHEBCHE | |
| Iodide SCHEMBL29462677 | 0.95 | ACHE (0.52) | ACHEBCHE | |
| Bromide SCHEMBL7776277 | 0.95 | ACHE (0.52) | ACHEBCHE | |
| Hydrochloric Acid SCHEMBL30383932 | 0.95 | ACHE (0.52) | ACHEBCHE | |
| Hydrochloric Acid SCHEMBL27855884 | 0.95 | ACHE (0.52) | ACHEBCHE | |
| Bromide SCHEMBL5611688 | 0.95 | ACHE (0.52) | ACHEBCHE | |
| Hydrochloric Acid SCHEMBL2031419 | 0.95 | ACHE (0.52) | ACHEBCHE | |
| Iodide SCHEMBL28357633 | 0.95 | ACHE (0.52) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114292267-B | Beta-carboline quinolinium salt with nitroreductase response as well as preparation method and application thereof | 南通大学 | 2024-03-08 | — | — | CN | claimed |
| WO-2015159122-A1 | NUCLEIC ACID BASED SENSOR AND METHODS THEREOF | NATIONAL CENTRE FOR BIOLOGICAL SCIENCES (IN) | 2015-10-22 | — | — | WO | claimed |
| US-8097756-B2 | Process for producing carboxylic acid anhydrides | CHINA PETROCHEMICAL DEVELOPMENT CORPORATION (TW) | 2012-01-17 | — | — | US | claimed |
| US-20100145098-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID ANHYDRIDES | CHINA PETROCHEMICAL DEVELOPMENT CORPORATION (TW) | 2010-06-10 | — | — | US | claimed |
| EP-1575539-A1 | DYE TABLETS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-09-21 | — | — | EP | claimed |
| WO-2004058202-A1 | DYE TABLETS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-07-15 | — | — | WO | claimed |
| EP-0458502-B1 | Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom | DOW GLOBAL TECHNOLOGIES INC (US) | 2003-06-18 | — | — | EP | claimed |
| EP-0476333-B1 | Process for simultaneous production of acetic acid and acetanhydride | HOECHST AG (DE) | 1994-11-30 | — | — | EP | claimed |
| US-5169473-A | Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability | THE DOW CHEMICAL COMPANY (US) | 1992-12-08 | — | — | US | claimed |
| EP-0476333-A2 | Process for simultaneous production of acetic acid and acetanhydride | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-25 | — | — | EP | claimed |
| EP-0458502-A2 | Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom | THE DOW CHEMICAL COMPANY (US) | 1991-11-27 | — | — | EP | claimed |
| US-4333884-A | Production of acetic anhydride | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-06-08 | — | — | US | claimed |
| US-4319038-A | BY REACTING METHYL ACETATE OR DIMETHYL ETHER WITH CARBON MONOXIDE AND HYDROGEN IN THE PRESENCE OF A CATALYST SYSTEM WHICH INCLUDES AN ALIPHATIC CARBOXYLIC ACID, A MANGANESE OR RHEMIUM COMPOUND, AND A HETEROCYCLIC NITROGEN-CONTAINING SALT | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-03-09 | — | — | US | claimed |
| EP-4551210-A1 | BIFACIAL PEPTIDE NUCLEIC ACID PROBES AND METHODS OF USING THEREOF | Ohio State Innovation Foundation (US) | 2025-05-14 | — | — | EP | disclosed |
| CN-119403778-A | Process for producing fluorinated organic compound | 大金工业株式会社 | 2025-02-07 | — | — | CN | disclosed |
| CN-114292267-B | Beta-carboline quinolinium salt with nitroreductase response as well as preparation method and application thereof | 南通大学 | 2024-03-08 | — | — | CN | disclosed |
| US-4333884-A | Production of acetic anhydride | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-06-08 | — | — | US | disclosed |
| US-4319038-A | BY REACTING METHYL ACETATE OR DIMETHYL ETHER WITH CARBON MONOXIDE AND HYDROGEN IN THE PRESENCE OF A CATALYST SYSTEM WHICH INCLUDES AN ALIPHATIC CARBOXYLIC ACID, A MANGANESE OR RHEMIUM COMPOUND, AND A HETEROCYCLIC NITROGEN-CONTAINING SALT | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-03-09 | — | — | US | disclosed |
| US-4304846-A | USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS | CIBA-GEIGY AG (CH) | 1981-12-08 | — | — | US | disclosed |
| US-4266011-A | FUSED PYRIDAZINE CATALYST | CIBA-GEIGY AG (CH) | 1981-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145098-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID ANHYDRIDES | CA4, CA9, CA7 | ACHE 2549/4885BCHE 979/4885KDM4E 947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.