Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPD1 | P10809 | 1/20 | 0.58 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.58 |
| ▸ | TTR | P02766 | 1/20 | 0.58 |
| ▸ | IGF1R | P08069 | 5/20 | 0.52 |
| ▸ | INSR | P06213 | 4/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.52 |
| ▸ | GSK3A | P49840 | 5/20 | 0.51 |
| ▸ | GSK3B | P49841 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.49 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.49 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.49 |
| ▸ | EIF4E | P06730 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364820 | 1.00 | HSPD1 (0.58) | HSPD1HSPE1TTRIGF1RINSR | |
| SCHEMBL12989659 | 1.00 | HSPD1 (0.58) | HSPD1HSPE1TTRIGF1RINSR | |
| SCHEMBL3364826 | 0.87 | TTR (0.55) | HSPD1HSPE1TTRIGF1RINSR | |
| SCHEMBL12990166 | 0.87 | TTR (0.55) | HSPD1HSPE1TTRIGF1RINSR | |
| SCHEMBL3364823 | 0.87 | TTR (0.55) | HSPD1HSPE1TTRIGF1RINSR | |
| SCHEMBL3892559 | 0.86 | HSPD1 (0.71) | HSPD1HSPE1TTRIGF1RINSR | |
| SCHEMBL3892565 | 0.86 | HSPD1 (0.71) | HSPD1HSPE1TTRIGF1RINSR | |
| SCHEMBL3363029 | 0.84 | MEN1 (0.58) | HSPD1HSPE1IGF1RINSRPIK3CG | |
| SCHEMBL12990164 | 0.84 | MEN1 (0.58) | HSPD1HSPE1IGF1RINSRPIK3CG | |
| SCHEMBL3363025 | 0.84 | MEN1 (0.58) | HSPD1HSPE1IGF1RINSRPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331315-A1 | RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS | SENHWA BIOSCIENCES, INC. (TW) | 2010-12-30 | — | — | US | disclosed |
| WO-2010148351-A1 | RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS | CYLENE PHARMACEUTICALS, INC. (US) | 2010-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331315-A1 | RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS | PIM2, PIM1, CDK2 | HSPD1 1307/4885HSPE1 1252/4885TTR 4754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.