Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 4/20 | 0.52 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.51 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.51 |
| ▸ | ITGAL | P20701 | 3/20 | 0.51 |
| ▸ | ECE1 | P42892 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3367983 | 0.99 | ALOX15 (0.55) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL2379077 | 0.93 | KMT2A (0.52) | ALOX15KMT2AOPRM1OPRL1MAPT | |
| SCHEMBL2379016 | 0.93 | KMT2A (0.52) | ALOX15KMT2AOPRM1OPRL1MAPT | |
| Hydrochloric Acid SCHEMBL2380910 | 0.92 | KMT2A (0.52) | ALOX15KMT2AOPRM1OPRL1MAPT | |
| Hydrochloric Acid SCHEMBL2379214 | 0.92 | KMT2A (0.52) | ALOX15KMT2AOPRM1OPRL1MAPT | |
| SCHEMBL2378536 | 0.90 | OPRL1 (0.49) | ALOX15ACEOPRM1OPRL1MAPK1 | |
| Hydrochloric Acid SCHEMBL2382884 | 0.89 | OPRL1 (0.48) | ALOX15ACEOPRM1OPRL1MAPK1 | |
| SCHEMBL2379397 | 0.84 | OPRL1 (0.58) | KMT2AOPRM1OPRL1MAPT | |
| SCHEMBL2378645 | 0.83 | MEN1 (0.43) | ALOX15ITGB2ICAM1ITGALKMT2A | |
| Hydrochloric Acid SCHEMBL303239 | 0.83 | OPRL1 (0.57) | KMT2AOPRM1OPRL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751093-B1 | SUBSTITUTED CYCLOHEXYLACETIC ACID DERIVATIVES | GRUENENTHAL GMBH (DE) | 2010-10-06 | — | — | EP | claimed |
| EP-1751093-B1 | SUBSTITUTED CYCLOHEXYLACETIC ACID DERIVATIVES | GRUENENTHAL GMBH (DE) | 2010-10-06 | — | — | EP | disclosed |