Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 4/20 | 0.31 |
| ▸ | BCHE | P06276 | 3/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 6/20 | 0.31 |
| ▸ | TP53 | P04637 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3365038 | 0.79 | MAPT (0.47) | DPP4PARP1LMNATHRBMAPT | |
| Hydrochloric Acid SCHEMBL3361686 | 0.79 | MAPT (0.47) | DPP4PARP1LMNATHRBMAPT | |
| SCHEMBL7720652 | 0.70 | MAPT (0.47) | DPP4LMNATHRBMAPTTP53 | |
| SCHEMBL8361297 | 0.69 | MAPT (0.46) | PARP1LMNATHRBMAPTTP53 | |
| SCHEMBL3361560 | 0.64 | DPP4 (0.74) | DPP4LMNASMN1; SMN2GAA | |
| SCHEMBL7721777 | 0.64 | MAPT (0.40) | PARP1LMNATHRBMAPTTP53 | |
| SCHEMBL3365420 | 0.63 | NPC1 (0.47) | DPP4LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL25389828 | 0.62 | DPP4 (0.47) | DPP4ALDH1A1 | |
| SCHEMBL3363380 | 0.61 | DPP4 (0.49) | DPP4LMNAMAPTALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3365128 | 0.61 | DPP4 (0.50) | DPP4MAPTALDH1A1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | claimed |