Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3365038 | 0.91 | MAPT (0.47) | MAPTALDH1A1POLBGAAHPGD | |
| Hydrochloric Acid SCHEMBL3361686 | 0.90 | MAPT (0.47) | MAPTALDH1A1POLBGAAHPGD | |
| SCHEMBL8361297 | 0.80 | MAPT (0.46) | MAPTALDH1A1POLBGAAHPGD | |
| SCHEMBL7721777 | 0.74 | MAPT (0.40) | MAPTALDH1A1POLBGAAHPGD | |
| SCHEMBL3365032 | 0.70 | DPP4 (0.43) | MAPTALDH1A1POLBGAAHPGD | |
| SCHEMBL3363380 | 0.69 | DPP4 (0.49) | MAPTALDH1A1GAAHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL3365128 | 0.69 | DPP4 (0.50) | MAPTALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL3365420 | 0.69 | NPC1 (0.47) | MAPTALDH1A1POLBGAAHTT | |
| SCHEMBL3364729 | 0.64 | DPP4 (0.50) | MAPTALDH1A1POLBGAAHTT | |
| SCHEMBL3361788 | 0.64 | DPP4 (0.61) | MAPTGAAHPGDHSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |