Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 19/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 19/20 | 0.73 |
| ▸ | DRD2 | P14416 | 16/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13114707 | 1.00 | DRD3 (0.73) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL3365350 | 1.00 | DRD3 (0.73) | DRD3KCNH2DRD2CYP1A2 | |
| Hydrochloric Acid SCHEMBL3422939 | 0.99 | DRD3 (0.72) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL3365070 | 0.96 | DRD3 (0.71) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL3365075 | 0.96 | DRD3 (0.71) | DRD3KCNH2DRD2CYP1A2 | |
| Hydrochloric Acid SCHEMBL3366090 | 0.95 | DRD3 (0.70) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL378630 | 0.94 | DRD2 (0.68) | DRD3KCNH2DRD2CYP1A2 | |
| Hydrochloric Acid SCHEMBL4433075 | 0.93 | DRD2 (0.67) | DRD3KCNH2DRD2CYP1A2 | |
| Hydrochloric Acid SCHEMBL4551295 | 0.93 | DRD2 (0.67) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL3364262 | 0.89 | DRD3 (0.79) | DRD3KCNH2DRD2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891056-B1 | NOVEL COMPOUNDS | GLAXO GROUP LTD (GB) | 2010-10-13 | — | — | EP | claimed |