SCHEMBL3365467

CCOc1ccc(S(=O)(=O)N(CC(=O)N/N=C2\C(=O)Nc3ccccc32)c2ccc(Cl)cc2)cc1.O=C(CN(c1ccc(Cl)cc1)S(=O)(=O)c1ccccc1)N/N=C1\C(=O)Nc2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	OXTR	P30559	4/20	0.58

▸	AVPR1A	P37288	4/20	0.58

▸	KMT2A	Q03164	5/20	0.51

▸	MEN1	O00255	4/20	0.51

▸	MAPT	P10636	4/20	0.49

▸	ALDH1A1	P00352	2/20	0.49

▸	CYP3A4	P08684	1/20	0.48

▸	CYP2C9	P11712	1/20	0.48

▸	CYP2C19	P33261	1/20	0.48

▸	POLB	P06746	2/20	0.47

▸	KDM4E	B2RXH2	1/20	0.47

▸	TP53	P04637	1/20	0.47

▸	THRB	P10828	1/20	0.47

▸	LMNA	P02545	1/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3365471	1.00	OXTR (0.58)	OXTRAVPR1AKMT2AMEN1MAPT
SCHEMBL3364643	0.98	OXTR (0.59)	OXTRAVPR1AKMT2AMEN1MAPT
SCHEMBL3370102	0.98	OXTR (0.59)	OXTRAVPR1AKMT2AMEN1MAPT
SCHEMBL3366189	0.94	MAPT (0.53)	OXTRAVPR1AKMT2AMEN1MAPT
SCHEMBL3366186	0.94	MAPT (0.53)	OXTRAVPR1AKMT2AMEN1MAPT
SCHEMBL3369773	0.94	MAPT (0.53)	OXTRAVPR1AKMT2AMEN1MAPT
SCHEMBL3364710	0.92	OXTR (0.52)	OXTRAVPR1AKMT2AMEN1MAPT
SCHEMBL3364706	0.92	OXTR (0.52)	OXTRAVPR1AKMT2AMEN1MAPT
SCHEMBL3365077	0.92	OXTR (0.52)	OXTRAVPR1AKMT2AMEN1MAPT
SCHEMBL3365082	0.92	OXTR (0.52)	OXTRAVPR1AKMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1335901-B1	PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES	MERCK SERONO SA (CH)	2010-04-14	—	—	EP	claimed