SCHEMBL3365474

SCHEMBL3365474

CCCCc1cccc(OC)c1O.Oc1ccccc1C1CCCCC1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.59
PTGS2 P35354 1/20 0.59
ELANE P08246 2/20 0.42
CTSG P08311 1/20 0.42
CNR2 P34972 4/20 0.40
CNR1 P21554 3/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40
ALOX12 P18054 1/20 0.40
MAPK1 P28482 1/20 0.40
HSD17B10 Q99714 1/20 0.40
HTR2A P28223 1/20 0.40
DRD2 P14416 1/20 0.40
TAS1R3 Q7RTX0 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3365472 0.87 CNR2 (0.42) ALOX5PTGS2CNR2CNR1DRD2
SCHEMBL10788064 0.81 ALOX5 (0.44) ALOX5PTGS2ELANECTSGCNR2
SCHEMBL28207413 0.80 BID (0.43) ALOX5CNR2CNR1TP53CYP3A4
SCHEMBL29365570 0.80 ALOX5 (0.90) ALOX5PTGS2ELANECTSGKDM4E
SCHEMBL59746 0.80 ALOX5 (0.90) ALOX5PTGS2ELANECTSGKDM4E
SCHEMBL27446430 0.79 BID (0.45) ALOX5CNR2CNR1TP53CYP3A4
SCHEMBL7210177 0.78 ALOX5 (0.87) ALOX5PTGS2ELANECTSGKDM4E
Alcohol SCHEMBL28456628 0.78 ALOX5 (0.87) ALOX5PTGS2ELANECTSGKDM4E
Orthocresol SCHEMBL28013940 0.78 ALOX5 (0.71) ALOX5PTGS2ELANECTSGKDM4E
Methoxymethane SCHEMBL10887589 0.77 KMT2A (0.49) PTGS2KDM4EALDH1A1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7709170-B2 Latent electrostatic image bearing member, and process cartridge, image forming apparatus and image forming method RICOH COMPANY, LTD. (JP) 2010-05-04 US disclosed
US-20060286473-A1 Latent electrostatic image bearing member, and process cartridge, image forming apparatus and image forming method RICOH COMPANY, LTD. (JP) 2006-12-21 US disclosed