⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL539633 | 0.79 | — | — | |
| SCHEMBL2872793 | 0.79 | — | — | |
| SCHEMBL29475125 | 0.79 | — | — | |
| SCHEMBL31555002 | 0.79 | — | — | |
| SCHEMBL24553668 | 0.75 | — | — | |
| SCHEMBL15228281 | 0.75 | — | — | |
| SCHEMBL2596902 | 0.75 | — | — | |
| SCHEMBL21598448 | 0.75 | — | — | |
| SCHEMBL21358439 | 0.75 | — | — | |
| SCHEMBL6484537 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125907-A1 | DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEIGENE, LTD. (KY) | 2023-07-06 | — | — | WO | disclosed |
| EP-4192831-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022206888-A1 | CDK2 INHIBITORS AND USE THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2022-10-06 | — | — | WO | disclosed |
| WO-2016054807-A1 | TrkA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF | MERCK SHARP & DOHME CORP. (US) | 2016-04-14 | — | — | WO | disclosed |
| CN-103547567-A | Hedgehog antagonists having zinc binding moieties | CURIS INC | 2014-01-29 | — | — | CN | disclosed |
| US-7709583-B2 | Sulfur-containing cyclic olefin resin and its production method | TOSOH CORPORATION (JP) | 2010-05-04 | — | — | US | disclosed |
| US-20090069503-A1 | SULFUR-CONTAINING CYCLIC OLEFIN RESIN AND ITS PRODUCTION METHOD | TOSOH CORPORATION (JP) | 2009-03-12 | — | — | US | disclosed |
| WO-2006113089-A2 | DIAGNOSIS BY DETERMINATION OF HYPERACTIVITY OR INCREASED EXPRESSION OF MEMBERS OF CELL SIGNALING PATHWAYS | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2006-10-26 | — | — | WO | disclosed |
| WO-2006056608-A2 | CARBONYLATION PROCESS AND CATALYST THEREFOR | PHOENIX CHEMICALS LIMITED (GB) | 2006-06-01 | — | — | WO | disclosed |
| EP-1006135-B1 | Conjugated N-fluoropyridinium salt-containing polymer and use of the same | DAIKIN IND LTD (JP) | 2003-02-12 | — | — | EP | disclosed |
| EP-0787719-B1 | CONJUGATED N-FLUOROPYRIDINIUM SALT POLYMER AND USE THEREOF | DAIKIN IND LTD (JP) | 2001-08-16 | — | — | EP | disclosed |
| EP-1006135-A1 | Conjugated N-fluoropyridinium salt-containing polymer and use of the same | DAIKIN INDUSTRIES, LIMITED (JP) | 2000-06-07 | — | — | EP | disclosed |
| US-5736274-A | ANODE ACTIVE MATERIAL AND SOLID ELECTROLYTE FOR BATTERIES; HIGH ELECTROMOTIVE FORCE; HIGH ENERGY DENSITY; POLLUTION CONTROL; FLUORINATING AGENTS; LOW INTERNAL RESISTANCE IN CHARGING AND DISCHARGING | DAIKIN INDUSTRIES, LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0787719-A1 | CONJUGATED N-FLUOROPYRIDINIUM SALT POLYMER AND USE THEREOF | DAIKIN INDUSTRIES, LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |