SCHEMBL6484537

SCHEMBL6484537

Cc1nccc(Cl)c1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30624505 1.00
SCHEMBL30319394 0.75
SCHEMBL2872793 0.75
SCHEMBL26967671 0.75
SCHEMBL2232005 0.75
SCHEMBL30605193 0.75
SCHEMBL3365653 0.75
SCHEMBL2762630 0.75
SCHEMBL31555002 0.75
SCHEMBL4478461 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114380738-A Synthetic method of 3-bromo-4-chloro-2-methylpyridine 都创(重庆)医药科技有限公司 2022-04-22 CN claimed
US-12600728-B2 Interleukin-17 inhibitors NOVARTIS AG (CH) 2026-04-14 US disclosed
CN-119912478-A Amino heteroaryl macrocyclic compounds, preparation method and application thereof 北京鞍石生物科技股份有限公司 2025-05-02 CN disclosed
US-20230391782-A1 INTERLEUKIN-17 INHIBITORS NOVARTIS AG (CH) 2023-12-07 US disclosed
WO-2023205465-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN VERTEX PHARMACEUTICALS INCORPORATED (US) 2023-10-26 WO disclosed
EP-4237417-A1 INTERLEUKIN-17 INHIBITORS Novartis AG (CH) 2023-09-06 EP disclosed
CN-116323596-A Interleukin-17 inhibitors 诺华股份有限公司 2023-06-23 CN disclosed
US-20230183264-A1 TYK2 INHIBITORS AND USES THEREOF SUDO BIOSCIENCES LIMITED (GB) 2023-06-15 US disclosed
WO-2022091056-A1 INTERLEUKIN-17 INHIBITORS NOVARTIS AG (CH) 2022-05-05 WO disclosed
CN-114380738-A Synthetic method of 3-bromo-4-chloro-2-methylpyridine 都创(重庆)医药科技有限公司 2022-04-22 CN disclosed
US-20030018026-A1 Novel tricyclic hydroxy carboxamides and derivatives thereof tocolytic oxytocin receptor antagonists WYETH (US) 2003-01-23 US disclosed
US-5877322-A Substituted pyridines, their preparation, and their use as pesticides and fungicides HOECHST SCHERING AGREVO GMBH (DE) 1999-03-02 US disclosed
US-5723450-A Substituted pyridines, their preparation, and their use as pesticides and fungicides HOECHST SCHERING AGREVO GMBH (DE) 1998-03-03 US disclosed
CN-1130901-A Substituted pyridines, their preparation and their use as pesticides and fungicides HOECHST SCHERING AGREVO GMBH (DE) 1996-09-11 CN disclosed
CN-1130900-A Substituted pyridines, their preparation and their use as pesticides and fungicides HOECHST SCHERING AGREVO GMBH (DE) 1996-09-11 CN disclosed
EP-0719256-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES Hoechst Schering AgrEvo GmbH (DE) 1996-07-03 EP disclosed
EP-0719257-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES Hoechst Schering AgrEvo GmbH (DE) 1996-07-03 EP disclosed
WO-1995007891-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES HOECHST SCHERING AGREVO GMBH (DE) 1995-03-23 WO disclosed
WO-1995007892-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES HOECHST SCHERING AGREVO GMBH (DE) 1995-03-23 WO disclosed
CN-1013445-B PROCESS FOR THE PREPARATION OF HETEROCYCLIC COMPOUNDS SMITH KLINE FRENCH LAB (GB) 1991-08-07 CN disclosed