SCHEMBL3365673

SCHEMBL3365673

O=C(CC(O)C(=O)OCC(F)(F)F)OCC(F)(F)F

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.59
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7488252 0.86 HTT (0.52) HTTMEN1ALDH1A1TSHRKMT2A
SCHEMBL975279 0.78 HTT (0.52) HTTTSHR
SCHEMBL2690771 0.77 HTT (0.50) HTTMEN1ALDH1A1TSHRKMT2A
SCHEMBL7417210 0.75 HTT (1.00) HTTMEN1ALDH1A1TSHRKMT2A
SCHEMBL7417213 0.75 HTT (1.00) HTTMEN1ALDH1A1TSHRKMT2A
SCHEMBL23004700 0.73 HTT (0.47) HTTMEN1ALDH1A1TSHRKMT2A
SCHEMBL974718 0.73 HTT (0.50) HTTMEN1ALDH1A1TSHRKMT2A
SCHEMBL7510764 0.72 HTT (0.54) HTTMEN1ALDH1A1TSHRKMT2A
SCHEMBL4951808 0.72 HTT (0.54) HTTMEN1ALDH1A1TSHRKMT2A
SCHEMBL17468953 0.72 HTT (0.45) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115583878-A Preparation method of 4,4,4-trifluorobutyric acid 山东华安新材料有限公司 2023-01-10 CN disclosed
US-9042802-B2 Image forming apparatus RICOH COMPANY, LTD. (JP) 2015-05-26 US disclosed
US-20140270874-A1 IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2014-09-18 US disclosed
US-8822118-B2 Toner, development agent, and image forming apparatus RICOH COMPANY, LTD. (JP) 2014-09-02 US disclosed
US-20130244154-A1 TONER, DEVELOPMENT AGENT, AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2013-09-19 US disclosed
EP-2109008-B1 Image formation method RICOH CO LTD (JP) 2013-08-14 EP disclosed
US-8338066-B2 Toner, process cartridge and method of forming image RICOH COMPANY, LTD. (JP) 2012-12-25 US disclosed
US-20100055603-A1 TONER, PROCESS CARTRIDGE AND METHOD OF FORMING IMAGE RICOH COMPANY, LTD., (JP) 2010-03-04 US disclosed
US-20090257792-A1 IMAGE FORMATION METHOD AND IMAGE FORMING APPARATUS RICOH COMPANY LIMITED (JP) 2009-10-15 US disclosed
EP-2109008-A1 Image formation method and image forming apparatus Ricoh Company, Ltd. (JP) 2009-10-14 EP disclosed
US-20090186289-A1 TONER, IMAGE FORMATION METHOD AND IMAGE FORMING APPARATUS RICOH COMPANY LIMITED (JP) 2009-07-23 US disclosed
US-20080176159-A1 TONER, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS RICOH COMPANY LIMITED (JP) 2008-07-24 US disclosed