Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.58 |
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.45 |
| ▸ | ATR | Q13535 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | HCK | P08631 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667564 | 0.83 | CLK4 (0.46) | ADORA2AADORA1CLK4ADORA2B | |
| SCHEMBL3397294 | 0.82 | HRH3 (0.51) | ADORA2AADORA1 | |
| SCHEMBL28663052 | 0.79 | ADORA2A (0.54) | ADORA2AADORA1CLK4ADORA2BPIK3CD | |
| SCHEMBL3364120 | 0.78 | EGLN2 (0.47) | ADORA2AADORA1 | |
| SCHEMBL4231695 | 0.78 | ADORA2A (0.50) | ADORA2AADORA1DHFRCLK4PIK3CD | |
| SCHEMBL3021383 | 0.76 | ADORA1 (0.59) | ADORA2AADORA1ADORA2B | |
| SCHEMBL20657755 | 0.76 | ADORA2A (0.60) | ADORA2AADORA1CLK4ADORA2BATR | |
| SCHEMBL1358503 | 0.76 | ADORA2A (0.60) | ADORA2AADORA1DHFRADORA2BXDH | |
| SCHEMBL30659761 | 0.76 | ADORA2A (0.60) | ADORA2AADORA1CLK4ADORA2BATR | |
| SCHEMBL3364838 | 0.75 | MAP3K14 (0.46) | ADORA2AADORA1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |