Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8842527 | 0.82 | KDM4C (0.44) | HRH3PTPN11GAAKDM1ACYP11B2 | |
| SCHEMBL3365760 | 0.82 | ADORA2A (0.58) | ADORA1ADORA2A | |
| SCHEMBL21121007 | 0.81 | KMT2A (0.47) | ADORA1ADORA2AKMT2ARPS6KA3 | |
| SCHEMBL30036994 | 0.81 | PDK1 (0.53) | PTPN11GAAKDM1ACYP11B2 | |
| SCHEMBL25552022 | 0.81 | PDK1 (0.53) | PTPN11GAAKDM1ACYP11B2 | |
| SCHEMBL3364120 | 0.80 | EGLN2 (0.47) | ADORA1ADORA2ACYP11B2NSD2 | |
| SCHEMBL21121008 | 0.78 | ADORA1 (0.42) | ADORA1ADORA2AKMT2ARPS6KA3 | |
| SCHEMBL3021383 | 0.78 | ADORA1 (0.59) | ADORA1ADORA2A | |
| SCHEMBL25560197 | 0.77 | PDK1 (0.39) | HRH3PTPN11GAAKDM1ACYP11B2 | |
| SCHEMBL3364838 | 0.77 | MAP3K14 (0.46) | HRH3ADORA1ADORA2ACYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |