Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 6/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21476134 | 0.82 | CYP2A6 (0.50) | SRCCYP11B1CYP11B2CYP2A6 | |
| SCHEMBL3399384 | 0.81 | LCK (0.46) | IRAK4DYRK1BDYRK1AKDR | |
| SCHEMBL21363954 | 0.78 | CYP2A6 (0.39) | MKNK1MKNK2SRCCYP2A6 | |
| SCHEMBL11653455 | 0.78 | MAP4K4 (0.54) | MEN1PSIP1AXLMKNK1MKNK2 | |
| SCHEMBL25221500 | 0.78 | CYP11B1 (0.49) | MEN1PSIP1AXLMKNK1MKNK2 | |
| SCHEMBL30549060 | 0.78 | CYP11B1 (0.49) | MEN1PSIP1AXLMKNK1MKNK2 | |
| SCHEMBL12577749 | 0.74 | CYP2A6 (0.54) | MKNK1MKNK2DYRK1ACYP11B1CYP11B2 | |
| SCHEMBL12577677 | 0.74 | BRD4 (0.42) | SRCCYP2A6 | |
| SCHEMBL16431919 | 0.74 | MAP4K4 (0.56) | MEN1PSIP1AXLMKNK1MKNK2 | |
| SCHEMBL30337602 | 0.73 | CYP11B1 (0.55) | MEN1PSIP1AXLMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |