Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12104804 | 0.81 | CYP2A6 (0.55) | LCKKDRJAK3MAPK14CTSD | |
| SCHEMBL3365805 | 0.81 | MEN1 (0.44) | KDRIRAK4DYRK1BDYRK1A | |
| SCHEMBL16702215 | 0.78 | CYP11B1 (0.51) | BACE1IRAK4ALOX5APFEN1DYRK1A | |
| SCHEMBL5109073 | 0.78 | CYP2A6 (0.51) | LCKKDRJAK3MAPK14CTSD | |
| SCHEMBL3366249 | 0.78 | USP7 (0.49) | KDRJAK3BACE1ALOX5APFEN1 | |
| SCHEMBL29939240 | 0.78 | CYP11B1 (0.51) | BACE1IRAK4ALOX5APFEN1DYRK1A | |
| SCHEMBL3363703 | 0.77 | PDGFRB (0.51) | ALOX5APFEN1CHRNB4CHRNA3ADORA2A | |
| SCHEMBL21364096 | 0.76 | ALOX5AP (0.41) | LCKKDRJAK3MAPK14CTSD | |
| SCHEMBL13870160 | 0.75 | HTR7 (0.45) | LCKKDRJAK3MAPK14CHRNB4 | |
| SCHEMBL29933950 | 0.75 | MKNK1 (0.51) | CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |